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TranscriptomicsRegulator trafficking on bacterial transcription units in vivo
The in vivo trafficking patterns on DNA by the bacterial regulators of transcript elongation Sigma70, Rho, NusA, and NusG and the explanation for high promoter-proximal levels or peaks of RNA polymerase (RNAP) are unknown. Genome-wide ChIP-chip on E. coli revealed distinct association patterns of r...
ORGANISM(S): Escherichia coli 
2010-05-14 | E-GEOD-13938 | biostudies-arrayexpress
TranscriptomicsRho directs widespread termination of intragenic and stable RNA transcription
The transcription termination factor Rho is a global regulator of RNA polymerase (RNAP). Although individual Rho-dependent terminators have been studied extensively, less is known about the sites of RNAP regulation by Rho on a genome-wide scale. Using chromatin immunoprecipitation and microarrays (...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-16562 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the microdissected colon epithelium are similar to those of intact colon in the Il10-/- mouse model of IBD
Epithelial cells play an important role in the protection of the colon mucosa from the resident microbiota and are involved in the initiation and maintenance of intestinal inflammation. LMD is a technique that allows the extraction of specific cell types, such as colonic epithelial cells, to analyse...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-39859 | biostudies-arrayexpress
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
GenomicsBMI EWAS summary stats
Summary statistics for a multi-cohort epigenome-wide association study. This includes summary statistics (effect-size, standard error, p-value) for 470,000 methylation markers.
EGAD00010001029 | EGA
GenomicsDNA methylation and the adverse metabolic outcomes of adiposity
Overweight and obesity affect ~1.5 billion people worldwide, and are major risk factors for type-2 diabetes (T2D), cardiovascular disease and related metabolic and inflammatory disturbances.1,2 Although the mechanisms linking adiposity to its clinical sequelae are poorly understood, recent studies s...
EGAS00001001922 | EGA
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
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