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GenomicsRegulation of Ptch1 expression in the limb
Ptch1 is a critical negative feedback regulator of the Hedgehog signaling and is upregulated in response to pathway activation. How tissue specific responses are mediated remains unknown. Here, we performed ChIP-seq analysis for epitope-tagged endogenous Gli3 protein to identify limb-specific bindin...
ORGANISM(S): Mus musculus 
2014-07-03 | E-GEOD-52939 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses to Sonic Hedgehog pathway stimulation in in vitro derived neural progenitors
The objective of this study was to identify genes regulated by Sonic Hedgehog pathway stimulation in neural progenitors. Paired (parallel culture) triplicates of neuralized embryoid body cultures with and without Shh pathway stimulation (Ag1.3-treatment)
ORGANISM(S): Mus musculus 
2012-12-15 | E-GEOD-42565 | biostudies-arrayexpress
UnknownDisruption of asxl1 results in myeloproliferative neoplasms in zebrafish.
Not available
S-EPMC6550042 | biostudies-literature
GenomicsChIP-seq analysis of Gli1 and Sox2 input to neural progenitor program and integration with actve histone marks
In the vertebrate neural tube, regional Sonic hedgehog (Shh) signaling invokes a time- and concentration-dependent induction of six different cell populations mediated through Gli transcriptional regulators. Elsewhere in the embryo, Shh/Gli responses invoke different tissue appropriate regulatory pr...
ORGANISM(S): Mus musculus 
2012-12-15 | E-GEOD-42132 | biostudies-arrayexpress
UnknownShort-form adaptive measure of financial toxicity from the Economic Strain and Resilience in Cancer (ENRICh) study: Derivation using modern psychometric techniques.
Not available
S-EPMC9409561 | biostudies-literature
TranscriptomicsTranscription profiling of human healthy subjects, patients with Crohns Disease, and patients with Ulcerative Colitis to compare PBMCs in inflammatory bowel disease
Comparison of PBMC transcriptional profiles in healthy subjects, patients with Crohn's Disease, and patients with Ulcerative Colitis
ORGANISM(S): Homo sapiens 
2007-09-07 | E-GEOD-3365 | biostudies-arrayexpress
Proteomics,MultiomicsMTB_hypoxia
LC-MS/MS of cultured Mycobacterium tuberculosis in a hypoxia/reaeration timecourse
ORGANISM(S): Mycobacterium Tuberculosis 
2013-12-31 | PAe004063 | PeptideAtlas
UnknownA benchmark of expert-level academic questions to assess AI capabilities.
Not available
S-EPMC12851929 | biostudies-literature
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownMapping the human genetic architecture of COVID-19.
Not available
S-EPMC8674144 | biostudies-literature
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