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GenomicsWhole Genome Bisulfite Sequencing of CLDN6High vs CLDN6Low Sorted EpiSCs and APSD, and WT vs Pbx1-KO EpiSCs
The experiment was designed to assess the DNA methylation differences between CLDN6Low vs CLDN6High EpiSCs and APSD, as well as WT vs Pbx1-KO EpiSCs. Based on analysis of RNAseq data and GO, we narrowed down our focus to DNA methylation effects influencing lineage biases. We performed WGBS analysi...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13574 | biostudies-arrayexpress
TranscriptomicsExpression profiling by high throughput sequencing (RNA sequencing)
RNAseq of CLDN6 sorted Epiblast Stem Cells (EpiSCs), WT vs Pbx1-KO lines in mouse embryonic stem cells (ES (2i/LIF and serum/LIF) and EpiSCs, as well as across differentiation (EpiSCs differentiated towards Posterior Primitive Streak (PPS) and Extraembryonic Mesoderm (ExM). Also EpiSCs treated with ...
ORGANISM(S): Mus musculus 
2024-11-29 | E-MTAB-13618 | biostudies-arrayexpress
TranscriptomicsMARS-seq Version 2
scRNA-seq procedure and analysis. ScRNA-seq was performed using the Massively Parallel Single-Cell RNA-sequencing technology (MARS-seq) as described by Jaitin et al., 2014 (PMID: 24531970) EpiSCs were seeded at ~6 x 103 cells/cm2 in 6-well cell-culture plates pre-coated with 15 µg/ml human Fibronec...
ORGANISM(S): Mus musculus 
2025-04-28 | E-MTAB-13660 | biostudies-arrayexpress
UnknownResident synovial macrophages in synovial fluid: Implications for immunoregulation.
Not available
S-EPMC12515479 | biostudies-literature
ProteomicsTop-down proteome of de-fatted Bos taurus milk from an animal with clinical mastitis
Quarter-milk samples were collected from a cow with clinical mastitis on day 13 and day 16 postpartum. Milk was collected from a clinical quarter with signs of abnormality (i.e., flakes, clots, blood) and one normal quarter of the same animal. Milk samples were processed with the MPLEx protocol (ht...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2022-02-09 | MSV000088805 | MassIVE
UnknownDesign and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial.
Not available
S-EPMC6888890 | biostudies-literature
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