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TranscriptomicsInfluence of low and high force muscle activity on paralyzed muscle gene expression
We used a novel approach to study the acute effect of two frequencies of stimulation (20 Hz and 5 Hz; high and low force, respectively) on gene regulation in people with chronic paralysis. Three hours after the completion of the electrical stimulation protocol (5 Hz or 20 Hz), we sampled the vastus ...
ORGANISM(S): Homo sapiens 
2015-08-01 | E-GEOD-64683 | biostudies-arrayexpress
UnknownImpact of Earlier Diagnosis in Cardiac ATTR Amyloidosis Over the Course of 20 Years.
Not available
S-EPMC9698091 | biostudies-literature
TranscriptomicsInhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia [Illumina HumanHT-12 gene expression array]
All-trans-retinoic acid (ATRA) has been successfully used in therapy of acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML) but the response of non-APL AML cases to ATRA-based treatment has been poor. Here we show that, via epigenetic reprogramming,...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-34672 | biostudies-arrayexpress
UnknownDiagnostic Value of Micro-Ultrasound in Identifying Local Recurrence After Radical Prostatectomy.
Not available
S-EPMC12704237 | biostudies-literature
TranscriptomicsSpatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation
Interaction of hematopoietic progenitors with the thymic stromal microenvironment induces them to proliferate, adopt the T cell fate, and asymmetrically diverge into multiple T lineages. Progenitors at various developmental stages are stratified among different regions of the thymus, implying that t...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-18281 | biostudies-arrayexpress
UnknownOptic neuropathy in a herd of beef cattle in Alberta associated with consumption of moldy corn.
Not available
S-EPMC4327135 | biostudies-literature
TranscriptomicsIdentification of E47 targets
In maturing T-lineage cells, the helix-loop-helix protein E47 has been shown to enforce a critical proliferation and developmental checkpoint commonly referred to as β selection. To examine how E47 regulates cellular expansion and developmental progression, we have used an E2A deficient lymphoma c...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4784 | biostudies-arrayexpress
UnknownMyotonic dystrophy type 1 alters muscle twitch properties, spinal reflexes, and perturbation-induced trans-cortical reflexes.
Not available
S-EPMC7711310 | biostudies-literature
GenomicsInhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia [ChIP-Seq]
All-trans-retinoic acid (ATRA) has been successfully used in therapy of acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML) but the response of non-APL AML cases to ATRA-based treatment has been poor. Here we show that, via epigenetic reprogramming,...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-34725 | biostudies-arrayexpress
UnknownType 1 diabetes patient experiences and management practices during the COVID-19 pandemic in rural Uganda.
Not available
S-EPMC10201465 | biostudies-literature
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