Sort   by:  
 Page size 
TranscriptomicsAffymetrix 6.0 SNP arrays interrogated to detect allele-specific DNA modification in the brain
It has long been hypothesized that knowledge of allele-specific modification (ASM; "modification" is used to denote various types of epigenetic cytosine marks, not only methylation) can supplement and inform GWAS of complex diseases and traits. To explore the relationship between GWAS subt...
ORGANISM(S): Homo sapiens 
2015-07-29 | E-GEOD-71443 | biostudies-arrayexpress
GenomicsEpigenetics of lactose intolerance and lactase persistence
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-03-25 | E-GEOD-69979 | biostudies-arrayexpress
GenomicsFine-mapping of DNA modifications in the lactase gene region of humans and mice
Bisulfite padlock probe technique was used to examine DNA modifications at the lactase gene region for human and mouse tissues DNA modifications were investigated in human sperm, blood, jejunal enterocytes and jejunum lacking enterocytes, as well as mouse jejunal enterocytes and jejunum lacking ente...
ORGANISM(S): Mus musculus 
2016-03-25 | E-GEOD-69977 | biostudies-arrayexpress
TranscriptomicsChromosome-wide DNA unmethylome profiling examining human chromosomes 2, 9, 19 and mouse chromosomes 1, 9, 19
The unmodified DNA fraction of jejunal enterocytes and the jejunum lacking enterocytes of humans and jejunal enterocytes of mice was interrogated on Affymetrix tiling arrays The mTAG technique was used to enrich the unmodified DNA fraction in a total of 56 humans and 26 mice
ORGANISM(S): Mus musculus 
2016-03-25 | E-GEOD-69972 | biostudies-arrayexpress
Genomics5-hmC in the brain: abundance in synaptic genes and differences at the exon-intron boundary (MRE-Seq)
5-hydroxymethylcytosine (5-hmC), a derivative of 5-methylcytosine (5-mC), is abundant in the brain for unknown reasons. We mapped the genomic distribution of 5-hmC and 5-mC in human and mouse tissues using glucosylation of 5-hmC coupled with restriction enzyme digestion, and interrogation on microar...
ORGANISM(S): Homo sapiens 
2012-08-24 | E-GEOD-40158 | biostudies-arrayexpress
TranscriptomicscirDNA methylome analysis in prostate cancer
DNA modification profiling of circulating DNA (cirDNA) from plasma samples from prostate cancer patients (T2-3N0Mx), benign prostatic hyperplasia and control individuals Epigenetic differences are a common feature of many diseases, including cancer, and disease-associated changes have even been dete...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-36195 | biostudies-arrayexpress
Sort   by:  
 Page size