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GenomicsGene expression profiles of PGAM5-knockout brown adipose tissue
Gene expression profiles of PGAM5-knockout brown adipose tissue
PRJNA577125 | ENA
GenomicsMitochondrial Phosphatase PGAM5 Negatively Regulates the Induction of Anti-inflammatory Macrophages
Mitochondrial Phosphatase PGAM5 Negatively Regulates the Induction of Anti-inflammatory Macrophages
PRJNA1439355 | ENA
TranscriptomicsGene expression profiles of PGAM5-knockout brown adipose tissue
PGAM5 is a mitochondria-localized protein phosphatase. To analyze the effect on gene expression profiles by PGAM5 in iBAT, RNA-seq analysis was performed.
ORGANISM(S): Mus musculus 
2019-10-12 | GSE138782 | GEO
TranscriptomicsMitochondrial Phosphatase PGAM5 Negatively Regulates the Induction of Anti-inflammatory Macrophages
Mitochondrial metabolism plays a crucial role in determining the functional polarization of macrophages, yet how mitochondrial signaling differentially regulates the induction of pro- and anti-inflammatory macrophages remains incompletely understood. Phosphoglycerate mutase 5 (PGAM5), a mitochondria...
ORGANISM(S): Mus musculus 
2026-04-04 | GSE325270 | GEO
GenomicsROS-induced cytosolic release of PGAM5 accelerates cancer progression via MST3-YAP axis
ROS-induced cytosolic release of PGAM5 accelerates cancer progression via MST3-YAP axis
PRJNA1043738 | ENA
TranscriptomicsContribution of STAT3, IRF1 and PGAM5 to androgen response in prostate cancer cells
To decipher the contribution of STAT3, IRF1 and PGAM5 to androgen-responsive gene expression, effect of siRNA-mediated silencing of STAT3, IRF1 and PGAM5 on expression of androgen-dependent genes was studied.
ORGANISM(S): Homo sapiens 
2017-05-01 | GSE81780 | GEO
GenomicsMitochondrial PGAM5−Drp1 signaling regulates the metabolic reprogramming of macrophages and regulates the induction of inflammatory responses
Mitochondrial PGAM5−Drp1 signaling regulates the metabolic reprogramming of macrophages and regulates the induction of inflammatory responses
PRJNA985681 | ENA
TranscriptomicsROS-induced cytosolic release of PGAM5 accelerates cancer progression via MST3-YAP axis
Aberrant mtROS release in response to mitochondrial stress are considered to be a major novel feature of neoplastic transformation. However, the molecular mechanisms by which mtROS contribute to CRC development have not been fully elucidated. In this study, we showed that upon sensing the mtROS sign...
ORGANISM(S): Mus musculus 
2024-11-05 | GSE248431 | GEO
TranscriptomicsMitochondrial PGAM5−Drp1 signaling regulates the metabolic reprogramming of macrophages and regulates the induction of inflammatory responses
Macrophages play a critical role in the regulation of inflammation and tissue homeostasis. In addition to their vital functions for cell survival and physiology, mitochondria play a crucial role in innate immunity as a platform for the induction of inflammatory responses by regulating cell signaling...
ORGANISM(S): Mus musculus 
2023-06-20 | GSE235306 | GEO
UnknownMitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
Not available
S-EPMC4725845 | biostudies-literature
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