Phagophore - OmicsDI

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CHEBI:140355 (1)

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PI(16:0/16:0) (2)
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18-hydroxyjacobine (1)
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Acetylseneciphylline (1)
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Lab affiliation

MRC - Laboratory of Molecular Biology (2)
Carnegie Mass Spec Facility (1)
Department of Biology,Washington University in St. Louis (1)
Department of Biomedical Science, University of Padova, via U. Bassi 58b, 35121 Padova, Italy. Venetian Institute of Molecular Medicine, via Orus 2, 35129 Padova, Italy Myology Center, University of Padova, via G. Colombo 3, 35100 Padova, Italy. Department of Medicine, McGill University, Montreal, Canada. Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, USA. (1)
Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine (1)
Harvard Medical School Department of Cell Biology Boston MA 02115, USA (1)
Institute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue Straße 15, 60438 Frankfurt am Main, Germany. Fraunhofer Institute of Translational Medicine and Pharmacology, Carl-von-Noorden-Platz 9, 60596 Frankfurt am Main, Germany (1)
Kobilka Institute of Innovative Drug Discovery, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Shenzhen 518172, China. (1)
Max Perutz Labs, Vienna BioCenter, Dr. Bohr-Gasse 9, Vienna, Austria (1)
SyNergy, LMU München (1)

Tags

xref:PubMed:41963349 (1)

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Establishment of the phagophore-ERES membrane contact site initiates phagophore elongation.

Not available

S-EPMC12618252 | biostudies-literature

Ultrastructural relationship of the phagophore with surrounding organelles.

Not available

S-EPMC4502653 | biostudies-literature

Morphology of Phagophore Precursors by Correlative Light-Electron Microscopy.

Not available

S-EPMC9562894 | biostudies-literature

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

Not available

S-EPMC7054675 | biostudies-literature

A GABARAP−PtdIns3K-C1 positive feedback loop at the heart of the phagophore nucleation

Macroautophagy/autophagy is a cellular process allowing the degradation of intracellular components during starvation. In mammalian cells, autophagosomes can reach over 1000 nm within 30 min after triggering starvation, but how such substantial amounts of membranes can be synthesized within a brief ...

ORGANISM(S): Homo sapiens (Human)

2026-07-02 | PXD074963 | Pride