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MetabolomicsLipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy
As a consequence of impaired glucose or fatty acid metabolism, bioenergetic stress in skeletal muscles may trigger myopathy and rhabdomyolysis. Genetic mutations causing loss of function of the LPIN1 gene frequently lead to severe rhabdomyolysis bouts in children, though the metabolic alterations an...
2019-01-07 | MTBLS750 | MetaboLights
TranscriptomicsA role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing
Epigenetic silencing of transposons by Piwi-interacting RNAs (piRNAs) constitutes an RNA-based genome defense mechanism. Piwi endonuclease action amplifies the piRNA pool by generating new piRNAs from target transcripts by a poorly understood mechanism. Here, we identified mouse Fkbp6 as a factor in...
ORGANISM(S): Bombyx mori 
2012-09-04 | E-GEOD-39203 | biostudies-arrayexpress
GenomicsTranscriptome analysis of Wild Type and RhoP23H/+ mouse retinal explant in presence of a pharmacological chaperone of rhodopsin, YC-001.
Transcriptome analysis of Wild Type and RhoP23H/+ mouse retinal explant in presence of a pharmacological chaperone of rhodopsin, YC-001.
PRJNA744905 | ENA
UnknownPharmacological Chaperone Therapy for Pompe Disease.
Not available
S-EPMC8659197 | biostudies-literature
UnknownPharmacological chaperone design for reducing risk factor of Parkinson's disease from traditional chinese medicine.
Not available
S-EPMC3914314 | biostudies-literature
UnknownUsing pharmacological chaperones to restore proteostasis.
Not available
S-EPMC4070435 | biostudies-literature
UnknownPharmacological targeting of the Hsp70 chaperone.
Not available
S-EPMC2799686 | biostudies-literature
UnknownA Pharmacological Chaperone Therapy for Acute Intermittent Porphyria.
Not available
S-EPMC7001003 | biostudies-literature
UnknownChaperone-Dependent Mechanisms as a Pharmacological Target for Neuroprotection.
Not available
S-EPMC9820882 | biostudies-literature
UnknownAmbroxol as a pharmacological chaperone for mutant glucocerebrosidase.
Not available
S-EPMC3547170 | biostudies-literature
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