Phelan Paul P - OmicsDI

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Genomics (3)
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Metabolite Name

2-Hydroxybutyric acid (2)
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Study type

Transcription profiling by array (1)

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2015 (8)
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Acute heat stress amplifies exercise-induced metabolomic perturbations and reveals variation in circulating amino acids in endurance-trained males

Using untargeted metabolomics, we aimed to characterise the systemic impact of environmental heat stress during exercise. Twenty-three trained male triathletes completed a 30-min exercise test in hot (35°C) and temperate (21°C) conditions. Venous blood samples were collected immediately pre- and ...

2025-08-14 | MTBLS6051 | MetaboLights

Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model

Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal poten...

2018-08-13 | MTBLS541 | MetaboLights

Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium.

Not available

S-EPMC3103497 | biostudies-literature

Growth factor independence 1 (Gfi1) as a new target for leukemia therapy

Using (conditional) Gfi1 knock-out mice we show that ablation of the transcriptional repressor Gfi1 cures mice from lymphoid leukemia and reduces the expansion of primary human T-ALL xenografts in mice. We find that Gfi1 alters the p53 dependent transcriptional activation of a substantial subset of ...

ORGANISM(S): Mus musculus

2012-10-03 | E-GEOD-32910 | biostudies-arrayexpress

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer.

Not available

S-EPMC4082406 | biostudies-literature

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome.

Not available

S-EPMC4000890 | biostudies-literature

Common variants at 19p13 are associated with susceptibility to ovarian cancer.

Not available

S-EPMC3125495 | biostudies-literature

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.