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TranscriptomicsTranscription profiling by array of Rattus norvegicus cardiomyocytes to investigate the effects of 30 or 60 min phenylephrine exposure on gene expression
Rat neonatal cardiomyocytes were exposed to 100 uM phenylephrine for 0, 30 or 60 mins
ORGANISM(S): Rattus norvegicus 
2013-01-16 | E-MEXP-3678 | biostudies-arrayexpress
TranscriptomicsLncRNA Chaer contributes to the transcriptome reprogramming during phenylephrine-induced hypertrophy in neonatal rat ventricular myocytes
We compared the transcriptome modified by siRNA-mediated cardiac hypertrophy associated epigenentic regulator (Chaer) with negative control siRNA treated neonatal rat ventricular myocytes with or without phenylephrine treatment. The results suggest that Chaer knockdown broadly blocks the phenylephri...
ORGANISM(S): Rattus norvegicus 
2016-06-30 | E-GEOD-82339 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat neonatal ventricular cardiomyocytes (NRVCMs) stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM
Neonatal rat ventricular cardiomyocytes (NRVCMs) were stretched biaxially (112%/24h) or stimulated with phenylephrine (PE, 50 uM), both resulting in a similar degree of hypertrophy. Unstretched NRVCMs served as negative control. Affymetrix microarray analysis revealed 164 genes more than 2.0-fold up...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5996 | biostudies-arrayexpress
TranscriptomicsTime Course of Gene Expression in Rat-1 Fibroblasts Following Alpha-1a Adrenergic Receptor Stimulation with Phenylephrine.
In mammals, increasing evidence supports the generality of cotranscriptional gene regulation and the idea that genetic control often occurs subsequent to RNA polymerase II (Pol II) recruitment. In our recent experiments, we have used Pol II Chromatin Immunoprecipitation (ChIP) to investigate relatio...
ORGANISM(S): Rattus rattus 
2014-08-01 | E-GEOD-59955 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neonatal rat ventricular myocytes treated with phenylephrine or PAMH
Neonatal rat ventricular myocytes cultured for 48 hours without stimulation, in the presence of twenty micromolar phenylephrine, or in the presence of one micromolar PAMH.
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-925 | biostudies-arrayexpress
Transcriptomicsin vivo 3-day RNA Seq: vehicle, angiotensin II, and phenylephrine
To analyze Gq-receptor hypertrophic transcriptional profiles, 10 to 11 week old FVB/NJ mice were dosed at 30 mg/kg/day for phenylephrine and 0.5 mg/kg/day for angiotensin II using implanted micro-osmotic pumps (Alzet, model 1002) for 72 hours. Total RNA was harvested from isolated myocytes using RNe...
ORGANISM(S): Mus musculus 
2018-05-12 | E-MTAB-6770 | biostudies-arrayexpress
TranscriptomicsA Comparison of Neonatal Rat Ventricular Myocytes Treated With Phenylephrine or PAMH
Neonatal rat ventricular myocytes cultured for 48 hours without stimulation, in the presence of twenty micromolar phenylephrine, or in the presence of one micromolar PAMH. Keywords = Rattus Keywords = Ventricular Myocytes Keywords = Cardiomyocytes Keywords = Hypertrophy Keywords = Phenylephrine Keyw...
ORGANISM(S): Rattus norvegicus 
2004-03-02 | GSE925 | GEO
TranscriptomicsLncRNA Chaer contributes to the transcriptome reprogramming during phenylephrine-induced hypertrophy in neonatal rat ventricular myocytes
We compared the transcriptome modified by siRNA-mediated cardiac hypertrophy associated epigenentic regulator (Chaer) with negative control siRNA treated neonatal rat ventricular myocytes with or without phenylephrine treatment. The results suggest that Chaer knockdown broadly blocks the phenylephri...
ORGANISM(S): Rattus norvegicus 
2016-06-30 | GSE82339 | GEO
Genomicsin vivo 3-day RNA Seq: vehicle, angiotensin II, and phenylephrine
in vivo 3-day RNA Seq: vehicle, angiotensin II, and phenylephrine
PRJEB26633 | ENA
GenomicsGene expression profiling of human-derived primary cardiomyocytes with lncRNA ZNF593-AS 5‘ end overexpression under phenylephrine stimulation
Gene expression profiling of human-derived primary cardiomyocytes with lncRNA ZNF593-AS 5‘ end overexpression under phenylephrine stimulation
PRJNA686998 | ENA
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