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GenomicsComparison of Transcription Profiles of M. smegmatis overexpressing wild type and phopshorylation defective PknK
Comparison of Transcription Profiles of M. smegmatis overexpressing wild type and phopshorylation defective PknK
PRJNA747928 | ENA
GenomicsERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex
ERK activates ERG-mediated prostate cancer specific gene expression program by phopshorylation induced dissociation of PRC2 complex
ORGANISM(S): Homo sapiens 
2018-02-13 | GSE86232 | GEO
TranscriptomicsIdentification of genes regulated by the phosphotylation of PPARgamma
In order to identify the molecular mechanisms of PPARgamma phosphorylation at Set273, we generated cell-lines of PPARgamma KO MEFs expressing wtPPARgamma or S273APPARgamma. In addition, because our data showed that PPARgamma ligand drugs such as rosiglitazone and MRL24 blocked this phopshorylation, ...
ORGANISM(S): Mus musculus 
2010-05-28 | GSE22033 | GEO
ProteomicsProteomics of TGF beta signaling
HaCaT cells were treated with TGF beta1 for different time points to follw protein and phosphoproteome changes on a temporal scale. Samples were analyzed using a shotgun proteomic approach on a Q exactive coupled to reverse phase HPLC. The measurements resulted in the identification of over 20,000...
ORGANISM(S): Homo sapiens (Human) 
2014-07-01 | PXD000496 | Pride
Temporal Mass spectrometry Phopshoproteome High resolution Tgf beta 
TranscriptomicsIdentification of genes regulated by the phosphotylation of PPARgamma
In order to identify the molecular mechanisms of PPARgamma phosphorylation at Set273, we generated cell-lines of PPARgamma KO MEFs expressing wtPPARgamma or S273APPARgamma. In addition, because our data showed that PPARgamma ligand drugs such as rosiglitazone and MRL24 blocked this phopshorylation, ...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-22033 | biostudies-arrayexpress
TranscriptomicsComparison of Transcription Profiles of M. smegmatis overexpressing wild type and phopshorylation defective PknK
We have shown that elevated levels of wild-type M. tuberculosis PknK (PknK Mtb), but not phosphorylation-defective PknKMtb, in Mycobacterium smegmatis cause significant retardation of growth rate and altered colony morphology (Malhotra et al., 2012). LIX79 (WT PknK) and LIX80 (PknK K55M mutant) M. s...
ORGANISM(S): Mycolicibacterium smegmatis 
2022-03-10 | GSE180348 | GEO
Unknownc-Abl phosphorylation of ΔNp63α is critical for cell viability.
Not available
S-EPMC3032504 | biostudies-literature
UnknownUnexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells.
Not available
S-EPMC2732704 | biostudies-literature
GenomicsHomo sapiens
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex
PRJNA340977 | ENA
UnknownConformational rearrangements upon Syk auto-phosphorylation.
Not available
S-EPMC2746503 | biostudies-literature
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