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Lysosomal Stress and Mitochondrial Dysfunction Define the Cellular Response to Photoactivated 1,9-Dimethyl-Methylene Blue
Microarrays of gene expression in mouse germinal center B cells photoactivated in the light zone or dark zone, and of naïve cells for comparison. We used microarray data to identify genes differentially expressed by B cells in the light and dark zones of the germinal center. Light and dark zone cell...
ORGANISM(S): Mus musculus 
Photodynamic therapy (PDT) using 1,9-dimethyl methylene blue (DMMB) induces coordinated mitochondrial and lysosomal damage and results in strong cellular death induction. However, the underlying transcriptional regulation in response to DMMB remains elusive. We compared the transcriptome response of...
ORGANISM(S): Homo sapiens 
2026-08-17 | GSE305949 | GEO
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