Sort   by:  
 Page size 
MetabolomicsPhyllosphere microbes mediate variety-specific accumulation of di-n-butyl phthalate in choysum (Brassica parachinensis)

Plant-microbe interactions in the phyllosphere have been demonstrated to facilitate plant growth and enhance resistance to diverse stresses; nevertheless, their role in the bioaccumulation of contaminants by plants is rarely considered. Here, by comparing differences in the phyllosphere morpholog...

2025-07-16 | MTBLS12464 | MetaboLights
MetabolomicsEnvironmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice
Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis, and linked to chronic diseases and developmental disorders. We used a community-level model of microbiota metabolism to investigate the effects of diethylhexyl phthalat...
2022-01-17 | MTBLS861 | MetaboLights
MetabolomicsCo-exposure of di(2-ethylhexyl) phthalate (DEHP) decreased the submicron plastic stress in soil-plant system

The widespread use of agricultural plastic films has made micro- and nanoplastics (MNPs) and phthalate esters (PAEs) contaminants of emerging concern in agroecosystems. However, the interactive mechanisms underlying their combined pollution in soil-plant systems remain elusive. To fill this gap, ...

2025-08-22 | MTBLS12878 | MetaboLights
MetabolomicsPlacental cells (BeWo) phthalate exposure metabolomics
Not available
ORGANISM(S): Homo sapiens 
ST000748 | MetabolomicsWorkbench
MetabolomicsChronic Exposure to Environmentally Relevant Doses of Butyl Benzyl Phthalate Promotes Development of Breast Tumor Via the Tricarboxylic Acid Cycle and Fatty Acid β-oxidation

This study investigates the proliferative effects of environmentally relevant exposure to butyl benzyl phthalate (BBP) on triple-negative breast cancer using integrated in vivo and in vitro approaches.

2025-12-06 | MTBLS13467 | MetaboLights
TranscriptomicsFetal Rat Testis mRNA Expression after 50 mg/kg Dibutyl Phthalate Exposure
High dose level dibutyl phthalate (DBP) exposure of fetal rat testes in vivo inhibits testosterone production (i.e. endocrine disruption). Here, fetal testis mRNA levels were profiled following exposure to a DBP dose level that did not significantly reduce testosterone levels. The goal was to iden...
ORGANISM(S): Rattus norvegicus 
2011-04-25 | E-GEOD-25196 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testes following exposure to mono-(2-ethylhexyl) phthalate
In rodent models, phthalate exposure alters both the fetal and pubertal testis, but the resulting histopathological changes are divergent. This suggests that the underlying molecular and cellular phthalate mechanism may be age-dependent. Using genome-wide expression profiling of acutely-exposed ra...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4514 | biostudies-arrayexpress
TranscriptomicsRole of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes
Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes related to nuclear receptor signaling. Di-(2-ethylhexyl)-phthalate (DEHP), a widely used plasticizer, is detected in consumer’s body fluids. Contamination occurs through environmental and food chain s...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-14920 | biostudies-arrayexpress
TranscriptomicsEffects of DEHP on the hepatic expression of a selection of mouse genes related to nuclear receptor signaling.
Phthalates are industrial additives widely used as plasticizers. In addition to deleterious effects on male genital development, population studies have documented correlations between phthalates exposure and impacts on reproductive tract development and on the metabolic syndrome in male adults. In ...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14629 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of di-n-butyl phthalate and 17α ethinyl-oestradiol responses in three-spined stickleback testes
The data comes from a study, where three-spined sticklebacks (Gasterosteus aculeatus) were exposed to di-n-butyl phthalate (DBP) and 17α ethinyl-oestradiol (EE2) at nominal concentrations 35 μg/L and 40 ng/L, respectively, for four days. The aim of the study was to obtain insight into the acute tran...
ORGANISM(S): Gasterosteus aculeatus 
2015-10-10 | E-MTAB-3951 | biostudies-arrayexpress
Sort   by:  
 Page size