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TranscriptomicsIdentification of renal distal convoluted tubules enriched genes
The renal distal convoluted tubule DCT is a short part of the distal nephron with specific functions transporting ions and thereby modifying Na, Ca, Mg, K balance A transcriptomic analysis of the DCT was performed to identify specific gene expression which would implicate those genes in specific DCT...
ORGANISM(S): Mus musculus 
2013-11-19 | E-GEOD-51935 | biostudies-arrayexpress
TranscriptomicsATAC-seq in the differentiation system ESC to NPC upon O-GlcNAc removal
This experiment uses a transgenic cell line expressing bacterial OGA BtGH84 fused to a localization peptide (NLS) and regulated by Tet-On system. OGA is a glycosidase that removes O-GlcNAc modifications. We evaluated the changes in chromatin openness before and after O-GlcNac removal by OGA.
ORGANISM(S): Mus musculus 
2024-08-31 | E-MTAB-14350 | biostudies-arrayexpress
GenomicsChIP-seq O-GlcNac in mouse ES cells
Analysis of O-GlcNac occupancy on chromatin in mouse ES cells by ChIP-seq
ORGANISM(S): Mus musculus 
2024-08-31 | E-MTAB-14310 | biostudies-arrayexpress
TranscriptomicsCutnRun of O-GlcNac in mouse ES cells in high glucose condition
Study of the chromatin occupancy of O-GlcNac in mouse ES cells cultivated in a high glucose concentration media
ORGANISM(S): Mus musculus 
2024-08-31 | E-MTAB-14308 | biostudies-arrayexpress
TranscriptomicsCutnRun of O-GlcNac in mouse ES cells in low glucose condition at 6 hours, 8 hours, and 1 week
Study of the chromatin occupancy of O-GlcNac in mouse ES cells cultivated in low glucose condition at 6 hours, 8 hours, and 1 week
ORGANISM(S): Mus musculus 
2024-08-31 | E-MTAB-14309 | biostudies-arrayexpress
TranscriptomicsCutnRun directed against O-GlcNac in the human DLD-1 cell line with doxycycline treatment to induce RNA Polymerase II degradation
This experiment aimed at investigating how O-GlcNac occupancy sites are impacted by RNA Polymerase II removal upon doxycycline stimulation. These human colon adenocarcinoma DLD-1 cells express OsTIR and a cassette encoding mini-AID (mAID) and fluorescent protein mClover (mAID+mClover) at the initiat...
ORGANISM(S): Homo sapiens 
2024-08-31 | E-MTAB-14307 | biostudies-arrayexpress
UnknownOVX033, a nucleocapsid-based vaccine candidate, provides broad-spectrum protection against SARS-CoV-2 variants in a hamster challenge model.
Not available
S-EPMC10319154 | biostudies-literature
GenomicsThe histone variant H2A.Z is an important regulator of enhancer activity.
Gene regulatory programs in different cell types are largely defined through cell-specific enhancers activity. The histone variant H2A.Z has been shown to play important roles in transcription mainly by controlling proximal promoters, but its effect on enhancer functions remains unclear. Here, we de...
ORGANISM(S): Homo sapiens 
2015-08-31 | E-GEOD-57436 | biostudies-arrayexpress
TranscriptomicsFunctional and transcriptional heterogeneity of human hemopoietic lympho-myeloid progenitors
Cord blood (CB) samples from normal donors were obtained with informed consent. Fresh CB samples were processed within 18-34h after collection. Mononuclear cells were isolated and CD34+ fraction was separated. CB CD34+ enriched fraction was lineage depleted by staining with purified anti-human CD2, ...
ORGANISM(S): Homo sapiens 
2017-10-03 | E-MTAB-5456 | biostudies-arrayexpress
UnknownAssociation of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19.
Not available
S-EPMC10219675 | biostudies-literature
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