Sort   by:  
 Page size 
MetabolomicsTissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment
The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...
2022-09-07 | MTBLS3873 | MetaboLights
MetabolomicsImpact of Diabetic Stress Conditions on Renal Cell Metabolome
Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria. Subsequently, albuminuria can deteriorate the ...
2019-10-08 | MTBLS1093 | MetaboLights
MetabolomicsMetabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)
Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...
2021-08-20 | MTBLS608 | MetaboLights
TranscriptomicsCircular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans.
Circular RNAs (circRNAs) are broadly expressed in eukaryotic cells, but their role in human health and disease remains obscure. Here, we show that circular antisense non-coding RNA in the INK4 locus (circANRIL), which is transcribed at a locus of atherosclerotic cardiovascular disease on chromosome ...
ORGANISM(S): Homo sapiens 
2016-08-22 | E-GEOD-65392 | biostudies-arrayexpress
Sort   by:  
 Page size