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TranscriptomicsFenofibrate increases VLDL-triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice
The PPAR? activator fenofibrate efficiently decreases plasma triglycerides (TG), which is generally attributed to enhanced VLDL-TG clearance and decreased VLDL-TG production. However, since data on the effect of fenofibrate on VLDL production are controversial, we aimed to investigate in (more) deta...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-21211 | biostudies-arrayexpress
TranscriptomicsPFOS and PFHxS decrease lipoprotein production
The effect of perfluoroalkyl sulfonates on lipoprotein metabolism was investigated in APOE*3-Leiden.CETP mice with a humanized lipoprotein profile. Perfluorohexane sulfonate and perfluorooctane sulfonate markedly reduced both plasma TG and TC by decreasing nonHDL-C and HDL-C accompanied by a reducti...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-22940 | biostudies-arrayexpress
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