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TranscriptomicsOrigin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp - single cell RNAseq dataset 1
Splenic white pulp (WP) structures are underpinned by fibroblastic stromal cells (FSCs) to facilitate splenic compartmentalization and execute efficient immune responses. Although distinct WP FSCs exhibit various molecular traits, the origin and the hierarchical differentiation of different cell sub...
ORGANISM(S): Mus musculus 
2019-03-27 | E-MTAB-7094 | biostudies-arrayexpress
TranscriptomicsFibroblastic reticular cells in the spleen - total splenic Stroma cells - single cell RNAseq dataset 2
Splenic white pulp (WP) structures are underpinned by fibroblastic stromal cells (FSCs) to facilitate splenic compartmentalization and execute efficient immune responses. Although distinct WP FSCs exhibit various molecular traits, the origin and the hierarchical differentiation of different cell sub...
ORGANISM(S): Mus musculus 
2019-03-27 | E-MTAB-7703 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of rat SJL sub-strains of an experimental autoimmune encephalomyelitis (EAE) rodent model of Multiple Sclerosis (MS)
Copy number variation in two SJL sub-strains of an experimental autoimmune encephalomyelitis (EAE) rodent model of Multiple Sclerosis (MS)
ORGANISM(S): Mus musculus 
2010-02-26 | E-MEXP-2534 | biostudies-arrayexpress
TranscriptomicsSingle cell RNAseq of immune and stromal cells in murine lung cancer
Immune responses against tumor cells depend on T lymphocyte attraction and activity within the tumor microenvironment. Specialized immune-interacting fibroblasts, commonly referred to as fibroblastic reticular cells (FRC), form specialized niches in secondary lymphoid organs, originate from embryoni...
ORGANISM(S): Mus musculus 
2024-11-19 | E-MTAB-13708 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of immune and stromal cells from the non small cell lung cancer (NSCLC) environment
T lymphocytes can efficiently counteract the growth of tumors within the tumor microenvironment. Specialized immune-interacting fibroblasts, termed fibroblastic reticular cells (FRC) are responsible for the formation of specialized niches promoting immune cell activation in secondary lymphoid organs...
ORGANISM(S): Homo sapiens 
2024-11-19 | E-MTAB-13710 | biostudies-arrayexpress
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