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TranscriptomicsTranscriptional profile of human breast cancer MCF7 cells and clones thereof expressing human ERβ1 or ERβ2 upon treatment with antiestrogens and retinoids.
The aim of the experiment was to gain insight into the role of estrogen receptor beta (ERβ) isoforms in the response of breast cancer MCF7 cells to antiestrogens and retinoids. To this end, clones of MCF7 cells constitutively expressing human ERβ1 (MCF7-ERβ1) or ERβ2 (MCF7-ERβ2) were established and...
ORGANISM(S): Homo sapiens 
2022-12-13 | E-MTAB-12549 | biostudies-arrayexpress
TranscriptomicsDecitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines
JIMT-1 and T-47D cell lines, were transfected with a DCK expression vector and exposed to low-dose decitabine (DAC). DAC, a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors.
ORGANISM(S): Homo sapiens 
2022-10-20 | E-MTAB-12224 | biostudies-arrayexpress
TranscriptomicsDecitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines
Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors.
ORGANISM(S): Homo sapiens 
2022-10-20 | E-MTAB-12225 | biostudies-arrayexpress
UnknownIRE1 activity prognosticates prostate cancer and is a mediator of epithelial lineage control.
Not available
S-SCDT-10_1038-S44321-026-00490-W | biostudies-other
UnknownControl of AGR2 dimerization links endoplasmic reticulum proteostasis to inflammation
Not available
S-SCDT-EMM-2018-10120 | biostudies-other
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