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The study was carried out to identify changes in expression of microRNAs in Neuro2A cells transfected with TATA binding protein (TBP) containing a polyglutamine expansion (59 glutamine-59Q) compared to normal TBP. Neuro2A cells were transfected in triplicate with either 16Q-TBP-GFP fusion or 59Q TBP...
ORGANISM(S): Mus musculus 
microRNAs play crucial roles in the early development of an organism. However the regulation of transcription through the action of microRNAs during the initial embyonic development has not been studied. We used microarrays to detail the effect of maternal microRNA mir-34 in regulation of zygotic t...
ORGANISM(S): Danio rerio 
Analysis of the effect of G-alpha or GPCR mutation on the Arabidopsis Transcriptome Keywords: Comparitive Genome Hybridization The transcriptomes of wild type and mutants (G-alpha and GPCR) were compared in the current study. The study was carried out on four whole genome oligo arrays. The G-alpha m...
ORGANISM(S): Arabidopsis thaliana 
HIV-1 Tat is a multifunctional protein, that in addition to its primary function of transactivating viral transcription also tends to modulate cellular gene expression, the molecular mechanism of which remains to be clearly elucidated. We have reported earlier NFκB enhancer binding activity of Tat ...
ORGANISM(S): Homo sapiens 
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