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TranscriptomicsTranscriptomics of vitamin D treatment effects in Mycobacterium tuberculosis-infected THP-1 cells
Previous reports have shown low vitamin D serum levels and polymorphisms in the vitamin D receptor (VDR) to be associated with increased risk for TB. Given that 1?,25-dihydroxyvitamin D3 has a role in lipid metabolism control, we tested whether the link between 1?,25-dihydroxyvitamin D3 and tubercul...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-57028 | biostudies-arrayexpress
TranscriptomicsPlatform comparison and transcription profiling of mixed tissue RNA samples formulated to contain different ratios of RNA for each of four rat tissues (brain, liver, kidney, and testes) on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays
This experiment is a test of a reagent that can provide a basis for performance assessments on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays. The reagent is a set of two mixed tissue RNA samples formulated to contain different ratios of RNA for each of f...
ORGANISM(S): Rattus norvegicus 
2010-03-30 | E-TABM-16 | biostudies-arrayexpress
TranscriptomicsSigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages
Sigma factor E (SigE) controls the expression of genes that are essential for Mtb virulence. In this work, we have identified the SigE regulon during infection of macrophages Our results indicate that SigE regulates the expression of genes involved in the maintenance of Mtb cell envelope integrity a...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-25 | E-GEOD-7962 | biostudies-arrayexpress
TranscriptomicsThe sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of human THP1 cells
Mycobacterium tuberculosis (Mtb) is well adapted to survive in macrophages and usually subverts the bactericidal mechanisms of these professional phagocytes. The adaptation of Mtb to the intracellular life depends on its ability to regulate the expression of its genes. Among the most important bact...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-7870 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of autumn senescence in populus Leaves
Gene expression profiling in leaves of a free-growing aspen tree (Populus tremula) in Umea in northern Sweden during natural autumn senescence (from August 17 to September 21).
ORGANISM(S): Populus tremula 
2004-03-09 | E-MEXP-93 | biostudies-arrayexpress
UnknownChanges in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A Scleroderma Patient-centered Intervention Network (SPIN) Cohort study.
Not available
S-EPMC7532799 | biostudies-literature
UnknownTitin-related familial dilated cardiomyopathy: factors associated with disease onset.
Not available
S-EPMC12718689 | biostudies-literature
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