Sort   by:  
 Page size 
UnknownA Systematic Review of the Level of Evidence in Economic Evaluations of Medical Devices: The Example of Vertebroplasty and Kyphoplasty.
Not available
S-EPMC4675526 | biostudies-literature
TranscriptomicsEffects of low and high doses of bisphenol A on mouse liver transcriptome
Bisphenol A (BPA) is used in the plastic industry as the monomer of polycarbonates and epoxy resins. Heat and changes in pH conditions lead to its leakage from the plastics in which it is incorporated. This largely contributes to the widespread exposure of the general population to this environmenta...
ORGANISM(S): Mus musculus 
2011-09-20 | E-GEOD-26728 | biostudies-arrayexpress
TranscriptomicsRole of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes
Role of PPARalpha in the effects of DEHP on the hepatic expression of a selection of mouse genes related to nuclear receptor signaling. Di-(2-ethylhexyl)-phthalate (DEHP), a widely used plasticizer, is detected in consumer’s body fluids. Contamination occurs through environmental and food chain s...
ORGANISM(S): Mus musculus 
2010-05-22 | E-GEOD-14920 | biostudies-arrayexpress
TranscriptomicsEffect of fipronil on the thyroid gland transcriptome in the rat
Fipronil is a widely-used broad-spectrum phenylpyrazole insecticide. It has been shown that fipronil increases the hepatic metabolism of thyroid hormone in the rat, which may induce compensatory mechanisms at the level of the thyroid gland itself. Here, we studied the effect of fipronil on the trans...
ORGANISM(S): Rattus norvegicus 
2016-09-07 | E-GEOD-75275 | biostudies-arrayexpress
TranscriptomicsHepatic transcriptome of rats treated with vehicle or fipronil (3 mg/kg/d per os for 14 days)
Fipronil (CAS #: 120068-37-3), a widely used insecticide, has been described as a thyroid disruptor in rat inducing a marked increase in thyroxine (T4) clearance resulting in a decrease in T4 plasma concentration. These effects seem to require the bioactivation of fipronil via its biotransformation ...
ORGANISM(S): Rattus norvegicus 
2013-08-22 | E-GEOD-39378 | biostudies-arrayexpress
TranscriptomicsEffects of DEHP on the hepatic expression of a selection of mouse genes related to nuclear receptor signaling.
Phthalates are industrial additives widely used as plasticizers. In addition to deleterious effects on male genital development, population studies have documented correlations between phthalates exposure and impacts on reproductive tract development and on the metabolic syndrome in male adults. In ...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14629 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human hepatocellular carcinoma samples shows miR-221 overexpression contributes to liver tumorigenesis
We profiled miRNA expression in tissue samples (104 HCC, 90 adjacent cirrhotic livers, 21 normal livers) as well as in 35 HCC cell lines. A set of 12 miRNAs (including miR-21, miR-221/222, miR-34a, miR-519a, miR-93,miR-96, and let-7c) was linked to disease progression from normal liver through cirrh...
ORGANISM(S): Homo sapiens 
2009-12-08 | E-TABM-866 | biostudies-arrayexpress
UnknownIdentification of Four Immune Subtypes Characterized by Distinct Composition and Functions of Tumor Microenvironment in Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC7589418 | biostudies-literature
TranscriptomicsIdentification of p53-regulated microRNAs in Hapatocellular Carcinoma (HCC).
p53 suppresses tumor progression and metastasis by regulating a large set of genes and microRNAs. By profiling 92 primary hepatocellular carcinomas (HCCs) and 9 HCC cell lines, we found that p53 upregulates microRNAs including miR-200 and miR-192 family members. By sequencing TP53 in 92 HCC samples,...
ORGANISM(S): Homo sapiens 
2011-05-11 | E-GEOD-28661 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human acute myeloid leukemia samples
AML
ORGANISM(S): Homo sapiens 
2010-05-10 | E-TABM-972 | biostudies-arrayexpress
Sort   by:  
 Page size