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GenomicsAccurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
Accurate functional annotation of regulatory elements is essential for understanding global gene regulation. Here, we report a genome-wide map of 827,000 transcription factor binding sites in human lymphoblastoid cell lines, which is comprised of sites correspond-ing to 239 position weight matrices ...
ORGANISM(S): Homo sapiens 
2010-11-15 | E-GEOD-25341 | biostudies-arrayexpress
UnknownClinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
Not available
S-EPMC3675667 | biostudies-literature
TranscriptomicsGenetic ancestry and natural selection drive population differences in immune responses to pathogens in humans
Individuals from different populations vary considerably in their susceptibility to immune-related diseases. To understand how genetic variation and natural selection contribute to these differences, we tested for the effects of African versus European ancestry on the transcriptional response of pri...
ORGANISM(S): Homo sapiens 
2016-09-06 | E-GEOD-81046 | biostudies-arrayexpress
GenomicsVariation in chromatin accessibility is a key determinant of heritable variation in gene expression
While it is well established that variation in gene expression levels can be influenced by single nucleotide polymorphisms (SNPs), little is known about the regulatory mechanisms by which this occurs. To address this gap, we used DNaseI sequencing to measure genome-wide chromatin accessibility in 70...
ORGANISM(S): Homo sapiens 
2012-01-26 | E-GEOD-31388 | biostudies-arrayexpress
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