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TranscriptomicsActivation of phosphatidylcholine-cycle enzymes in human epithelial ovarian cancer cells
Altered phosphatidylcholine (PC) metabolism in epithelial ovarian cancer (EOC) can provide choline-based imaging approaches as powerful tools to improve diagnosis and identify new therapeutic targets. Biochemical, protein and mRNA expression analyses demonstrated that the increase in the major choli...
ORGANISM(S): Homo sapiens 
2009-12-07 | E-GEOD-19352 | biostudies-arrayexpress
TranscriptomicsAberrant choline metabolism in epithelial ovarian cancer: relevance of choline kinase activity and expression
Detection of the abnormal phosphatidylcholine (PtdCho) metabolism in EOC by analysis of magnetic resonance profile (MRS), showed a significant increase of PCho content in EOC cells as compared with non tumoral counterparts associated with activation of choline kinase (ChoK), the enzyme responsible f...
ORGANISM(S): Homo sapiens 
2014-01-23 | E-GEOD-39943 | biostudies-arrayexpress
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