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TranscriptomicsTranscription profiling of moise placentae (E10.5) from adra2bKO and adra2bWT mutants
alpha2-adrenoceptors are essential presynaptic regulators of norepinephrine release from sympathetic nerves. Previous studies in mice with targeted deletions in the three alpha2-adrenoceptor genes have indicated that these receptors are essential for embryonic development. In the present study, we s...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6909 | biostudies-arrayexpress
TranscriptomicsGene expression in E18.5 Tex19.1-/- mouse placenta
Microarray experiment to identify changes in gene expression in 18.5 day post coitum Tex19.1-/- mouse placenta. Tex19.1 is expressed in trophectoderm-derived cells in the placenta. Tex19.1-/- placentas are small and have defects in junctional zone and labyrinth layers of the placenta, Tex19.1-/- emb...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-41823 | biostudies-arrayexpress
TranscriptomicsHeme-Bound Iron Activates Placenta Growth Factor via Erythroid KrM-CM-
We have tested the effect of iron on the gene expression profile in human leukemia cells with properties of erythroid differentiation. 12 Total samples were analyzed. We compared the gene expression profiles of cells treated with iron mesoporphyrin to mesoporphyrin alone. DMSO vehicle was also teste...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-52087 | biostudies-arrayexpress
GenomicsVariation in placenta-specific genomic imprinting is associated with intrauterine growth restriction.
Variation in placenta-specific genomic imprinting is associated with intrauterine growth restriction.
PRJNA495170 | ENA
TranscriptomicsIGR_SYNCYTINB_STUDY_AD
In most mammalian species, a critical step of placental development is the fusion of trophoblast cell into a multinucleated syncytiotrophoblast layer, which separates the fetal and maternal blood circulations. Advancement in understanding this process came from the identification of two pairs of env...
ORGANISM(S): Mus musculus 
2011-10-19 | E-TABM-1188 | biostudies-arrayexpress
TranscriptomicsCpG Island methylation variation in placentae of Intra-Uterine Growth Restricted (IUGR) fetuses versus controls
Methylation profiling of CpG Island Methylation of genomic DNA samples extracted from placentae of Intra-Uterine Growth Restricted newborns and gestational age matched controls. These data can be used for methylation comparisons between these two types of samples. The results of such comparisons can...
ORGANISM(S): Homo sapiens 
2011-04-11 | E-GEOD-22326 | biostudies-arrayexpress
GenomicsPlacenta insufficiency caused by abnormal folate metabolism linked to fetal growth restriction across gestation and generations [RNA-Seq]
Placenta insufficiency caused by abnormal folate metabolism linked to fetal growth restriction across gestation and generations [RNA-Seq]
PRJNA976334 | ENA
TranscriptomicsMicroarray analysis of gene expression profiles in Map2k1+/-Map2k2+/- and Map2k1flox/-Map2k2+/-Tg+/Sox2Cre placentas
The mammalian genome contains two ERK/MAP kinase kinase genes, Map2k1 and Map2k2, encoding dual-specificity kinases responsible for ERK/MAP kinase activation. Loss of Map2k1 function in mouse causes embryonic lethality due to placental defects, while Map2k2 mutant mice survive with a normal lifespan...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-51644 | biostudies-arrayexpress
Methylation profilingVariation in placenta-specific genomic imprinting is associated with intrauterine growth restriction.
The placenta has a critical role in fetal growth, with many key functions regulated by genomic imprinting. With the recent description of polymorphic placenta-specific imprinting, the molecular mechanisms leading to this curious epigenetic phenomenon are unknown, as is their involvement in pregnanci...
ORGANISM(S): Homo sapiens 
2019-02-05 | GSE120981 | GEO
UnknownNanoparticle-mediated transgene expression of insulin-like growth factor 1 in the growth restricted guinea pig placenta increases placenta nutrient transporter expression and fetal glucose concentrations.
Not available
S-EPMC10947605 | biostudies-literature
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