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The aim of this microarray experiment was to compare the overall transcriptomic profile of human placenta derived trophoblast organoid cultures with its tissue of origin, human placental villi. As the placental villi contains both trophoblast and stromal populations, we have included placenta derive...
ORGANISM(S): Homo sapiens 
Whole-transcriptome profiles of individual human placental villi samples from twenty-five (25) Indian women with normal pregnancies during 6- to 8-weeks of gestation were examined using human whole genome expression arrays (NimbleGen 135K). The present study focused on the whole-transcriptome profil...
ORGANISM(S): Homo sapiens 
To identify the proteins and molecular signaling pathways that contribute to EPL, we performed proteomics and bioinformatics analysis of the placental villi in women who have undergone EPL and in normal pregnant women.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080693 | MassIVE
Total RNAs extracted from placental villi collected from women with (vaginal delivery) or without labor (cesarean section) at term (37-42 weeks of gestation) were hybridized to ClariomD microarrays and analyzed at the gene level to evaluate differential expression genes postlabor
ORGANISM(S): Homo sapiens 
To identify the proteins and molecular signaling pathways that contribute to EPL, we performed proteomics and bioinformatics analysis of the placental villi in women who have undergone EPL and in normal pregnant women.
ORGANISM(S): Homo sapiens (Human) 
2016-03-11 | PXD002391 | Pride
Miscarriage occurs in 15-20% of clinical pregnancies. While chromosomal errors are observed in over 50%, causes of karyotypically normal losses are poorly understood. DNA methylation undergoes reprogramming during development and must be appropriately set to maintain a healthy pregnancy. We hypothes...
ORGANISM(S): Homo sapiens 
Gene expression profiling of placental villi from intrauterine and tubal ectopic pregnancies
Gene expression profiling of placental villi from intrauterine and tubal ectopic pregnancies
The role of placental macrophages is largely ignored in the success of pregnancy. We found that CD14+ macrophages purified from at-term placentas spontaneously matured into multinucleated giant cells (MGCs). MGCs lost the expression of CD14 and co-inhibitory molecules, such as Programmed cell Death-...
ORGANISM(S): Homo sapiens 
The human intraplacental environment undergoes major changes at the end of the first trimester associated with onset of the maternal blood flow. We collected placental villi samples before and after maternal blood flow to profile methylation changes at this crucial time window.
ORGANISM(S): Homo sapiens 
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