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GenomicsPlastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
Plastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
PRJNA811425 | ENA
TranscriptomicsPlastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
Spinal muscular atrophy (SMA) is a lethal pediatric neuromuscular disease caused by loss of the Survival Motor Neuron 1 gene (SMN1). Although current therapies focus very efficiently on SMN restoration, the cellular mechanisms underlying the pathological features are not fully understood. Smn-defici...
ORGANISM(S): Mus musculus 
2023-01-05 | GSE197638 | GEO
UnknownPlastin 3 in X-Linked Osteoporosis: Imbalance of Ca2+-Dependent Regulation Is Equivalent to Protein Loss.
Not available
S-EPMC7859272 | biostudies-literature
UnknownActin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis.
Not available
S-EPMC4550371 | biostudies-literature
UnknownPlastin 3 in health and disease: a matter of balance.
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S-EPMC8257523 | biostudies-literature
UnknownPlastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy.
Not available
S-EPMC4908855 | biostudies-literature
UnknownOsteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling.
Not available
S-EPMC7244493 | biostudies-literature
UnknownOverexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier.
Not available
S-EPMC4972356 | biostudies-literature
UnknownThe Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia.
Not available
S-EPMC6895973 | biostudies-literature
UnknownPlastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy.
Not available
S-EPMC9827530 | biostudies-literature
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