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TranscriptomicsDevelopmental trajectories of gene expression reveal candidates for diapause termination, a key life history transition in the apple maggot fly, Rhagoletis pomonella
Gene expression microarray experiment comparing differential expression across a developmental and metabolic trajectory of diapause termination. Six phenotypes representing 6 developmental time points, four replicate individuals for each phenotype, four competitve hybridizations for each of six phen...
ORGANISM(S): Rhagoletis pomonella 
2011-09-30 | E-GEOD-30785 | biostudies-arrayexpress
GenomicsPlat safeguards aged mouse oocytes against programmed cell death through activating the Erk1/2 pathway
Plat safeguards aged mouse oocytes against programmed cell death through activating the Erk1/2 pathway
PRJNA1183336 | ENA
TranscriptomicsRNAseq analysis of two independent stains of C57BL/6J-Plat-/- mice and wild-type C57BL/6J.
The ability to generate defined null mutations in mice revolutionized the analysis of gene function in mammals. However, gene-deficient mice generated by using 129-derived embryonic stem (ES) cells may carry large segments of 129 DNA, even when extensively backcrossed to reference strains, such as C...
ORGANISM(S): Mus musculus 
2016-12-16 | GSE76093 | GEO
TranscriptomicsSM009 - SARS infection of C57BL6, and PLAT knock-out mice.
This purpose of this experiment was to investigate the transcriptional differences between C57BL6, PLAT knock-out mice infected with SARS MA15 virus. Overview of Experiment: Groups of 20 week old C57BL6 and PLAT knock-out mice were infected with SARS MA15 virus. Infections were done at 10^5 PFU or t...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-51387 | biostudies-arrayexpress
TranscriptomicsSM009 - SARS infection of C57BL6, and PLAT knock-out mice.
This purpose of this experiment was to investigate the transcriptional differences between C57BL6, PLAT knock-out mice infected with SARS MA15 virus.
ORGANISM(S): Mus musculus 
2014-02-20 | GSE51387 | GEO
UnknownKnockdown of PLAT enhances the anticancer effect of gefitinib in non-small cell lung cancer.
Not available
S-EPMC7139041 | biostudies-literature
UnknownThrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia.
Not available
S-EPMC9225202 | biostudies-literature
GenomicsTranscriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drugs [Plat-RNAseq A549]
Transcriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drugs [Plat-RNAseq A549]
PRJNA1365917 | ENA
GenomicsTranscriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drug [Plat-RNAseq cPDS]
Transcriptome-wide mapping reveals an RNA-dependent mechanism of platinum cancer drug [Plat-RNAseq cPDS]
PRJNA1365911 | ENA
TranscriptomicsPlat safeguards aged mouse oocytes against programmed cell death through activating the Erk1/2 pathway
Female reproductive aging is characterized by the decline in oocytes quality and developmental potentials, but the underlying mechanisms remain insufficiently investigated. In this study, we analyze the transcriptomes of individual oocytes from young and aged mice, identifying a distinct group of ag...
ORGANISM(S): Mus musculus 
2025-09-13 | GSE281294 | GEO
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