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TranscriptomicsTranscription profiling of human HepG2 cells overexpressing GPI-phospholipase D vs control sampled at 2 time points
A time course of the effect of overexpressing GPI-PLD on global gene expression in HepG2 cells was compared to control virus. Experiment Overall Design: This experiment compares the global gene expression in HepG2 cells that were either transduced with an adenovirus expressing GPI-phospholipase D or...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4731 | biostudies-arrayexpress
TranscriptomicsGene expression profiling from pooled samples of subcutaneous adipose tissue of NAPE-WT or NAPE-KO mice fed either with a control diet or a high-fat diet.
Mice knocked-out or wild type for the NAPE PLD gene specifically in adipose tissue, were recruited for this expression profiling experiment. Each group of mice (WT versus cKO) were fed with a control diet or a high fat diet. Then mice were sacrificed and adipose tissue samples form the subcutaneous ...
ORGANISM(S): Mus musculus 
2015-03-06 | E-GEOD-56852 | biostudies-arrayexpress
GenomicsTranscriptomic data of parent and NAPE-PLD deteled Caco-2 cells
Transcriptomic data of parent and NAPE-PLD deteled Caco-2 cells
PRJNA477784 | ENA
ProteomicsDiscovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
N‑acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids. Using a high-through...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD017586 | Pride
Lipids Drug discovery Endocannabinoids Chemical biology 
Genomics
PLD-Imposed cell sequencing
PRJNA526479 | ENA
TranscriptomicsTranscriptomic data of parent and NAPE-PLD deteled Caco-2 cells
PURPOSE: We generated NAPE-PLD-deleted Caco-2 cells, which is a model of intestinal epithelial cells, using genome editing with the CRISPR/Cas9 system. To explore the molecular events following the deletion of NAPE-PLD in Caco-2 cells, we examined the transcriptomic changes in the NAPE-PLD deleted c...
ORGANISM(S): Homo sapiens 
2021-06-23 | GSE116213 | GEO
UnknownBile Acid Recognition by NAPE-PLD.
Not available
S-EPMC5074845 | biostudies-literature
TranscriptomicsEffect of GPI-PLD on global gene expression in HepG2 cells
A time course of the effect of overexpressing GPI-PLD on global gene expression in HepG2 cells was compared to control virus. Keywords: Expression profiling
ORGANISM(S): Homo sapiens 
2006-06-01 | GSE4731 | GEO
UnknownData on prior pegylated liposomal doxorubicin (PLD) treatment in recurrent ovarian cancer: Post-hoc data analysis from the phase 3 randomized, open-label study comparing trabectedin and PLD versus PLD alone in patients with recurrent ovarian cancer.
Not available
S-EPMC7178483 | biostudies-literature
UnknownHepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism.
Not available
S-EPMC7291298 | biostudies-literature
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