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Brain tumors are the second most common pediatric cancer and carry the highest mortality rates in this age group. Medulloblastoma is the most frequent malignant brain tumor of childhood. Recent studies indicate that medulloblastoma comprises at least four sub-entities (SHH-signaling, WNT-signali...
ICGC Germany PedBrain Medulloblastoma Pilot_2_LM
release_2: ICGC PedBrain: whole exome sequencing and Target-Seq
release_2: ICGC PedBrain: RNA sequencing
Whole genome bisulfite sequencing of pedbrain - medulloblastoma
4C-seq data was generated for regions of interest to confirm enhancer-gene promoter interactions
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed.
release_2: ICGC PedBrain: whole genome sequencing
release_2: ICGC PedBrain: whole genome bisulfite sequencing
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