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MetabolomicsEvidence that COG0325 proteins are involved in PLP homeostasis
Not available
ORGANISM(S): Escherichia coli 
ST000884 | MetabolomicsWorkbench
GenomicsTranscritome profiling of plp-1-mutant Caenorhabditis elegans
Transcritome profiling of plp-1-mutant Caenorhabditis elegans
PRJNA675108 | ENA
ProteomicsSLC25A38 is Required for Mitochondrial Pyridoxal 5’-Phosphate (PLP) accumulation
Many essential proteins require pyridoxal 5’-phosphate (PLP), the active form of vitamin B6, as a cofactor for activity including enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and neurotransmitter metabolism. A third of all mammalian PLP-...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058312 | Pride
Slc25a38 Mito ip Proliferation defects Lc-ms/ms 
GenomicsRNA-seq profiles of brains of Qk-Plp-iCKO mice and control mice.
RNA-seq profiles of brains of Qk-Plp-iCKO mice and control mice.
PRJNA606058 | ENA
TranscriptomicsTranscritome profiling of plp-1-mutant Caenorhabditis elegans
Through high-throuhgput RNA-sequencing, this study identifies mRNAs that are differentially expressed between plp-1(ok2155) and wild-type C. elegans. Analysed results are published in Development. 2020 Oct 13:dev.195578. doi: 10.1242/dev.195578. PMID: 33051256 Abstract of the publication: The germ l...
ORGANISM(S): Caenorhabditis elegans 
2020-11-07 | GSE161011 | GEO
TranscriptomicsRNA-seq profiles of brains of Qk-Plp-iCKO mice and control mice.
This study is to analyze the transcriptomic profiles of Plp-CreERT2;QkLoxP/LoxP (Qk-Plp-iCKO) mice and littermate controls to determine the differentially expressed genes after Qk deletion.
ORGANISM(S): Mus musculus 
2021-02-07 | GSE145116 | GEO
TranscriptomicsDifferential expression of genes in spinal cord folowing experimental autoimmune encephalomyelitis (EAE) in mice.
Microarrays were used to identify genes that were differently expressed in mouse spinal cord as a resut of experimental autoimmune encephalomyelitis (EAE), which is a model for demyelinating disease. Mice were injected with PLP peptide or vechicle.
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-44989 | biostudies-arrayexpress
GenomicsBulk mRNAseq in control and Plp-CreER_Ddx20 cKO mouse spinal cords
Bulk mRNAseq in control and Plp-CreER_Ddx20 cKO mouse spinal cords
PRJNA1217338 | ENA
Genomics
PEDV PLP-ORF3 sequencing
PRJNA1202675 | ENA
UnknownConformational change of organic cofactor PLP is essential for catalysis in PLP-dependent enzymes.
Not available
S-EPMC9537024 | biostudies-literature
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