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Embryonic stem cells (ESC) are able to give rise to any somatic cell type. A lot is known about how ESC pluripotency is maintained, but comparatively less is known about how differentiation is promoted. Cell fate decisions are regulated by interactions between signalling and transcriptional networks...
ORGANISM(S): Mus musculus 
The asynchrony in the exit from naive pluripotency cannot be explained by differences in the cell cycle phase
The asynchrony in the exit from naive pluripotency cannot be explained by differences in the cell cycle phase
Mesenchymal-Epithelial Transition Regulates Initiation of Pluripotency Exit before Gastrulation
Although much is known about the pluripotency self-renewal circuitry, the molecular events that lead embryonic stem cells (ESCs) exit from pluripotency and begin differentiation are largely unknown. We found that the zinc finger transcription factor Snai1, involved in gastrulation and epithelial- me...
ORGANISM(S): Mus musculus 
Chromatin activity of IκBα mediates the exit from naïve pluripotency (RNA-Seq)
Nanoscale Dynamics of Enhancer-Promoter Interactions during Exit from Pluripotency
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