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TranscriptomicsGene expression profile of mutated and wild-type PMF CD34+ cells
Primary mielofibrosis (PMF) is a rare chronic myeloproliferative disorder characterized by the accumulation of abnormal megakaryocytes (Mks) in the bone marrow (BM), variable degrees of BM fibrosis, osteosclerosis and angiogenesis, immature myeloid and erythroid cells, and tear-drop erythrocytes in ...
ORGANISM(S): Homo sapiens 
2013-07-23 | E-GEOD-41812 | biostudies-arrayexpress
TranscriptomicsIntegrative Analysis of Gene and miRNA expression profiles in Primary Myelofibrosis CD34+ cells
Ph-negative myeloproliferative neoplasms (MPNs) are characterized by many somatic mutations which have already been shown useful in the prognostic assessment of MPN patients. Moreover, aberrant microRNA (miRNA) expression seems to add to the molecular complexity of MPNs, as specific miRNA signatures...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-53482 | biostudies-arrayexpress
GenomicsMethylation profiles of PMF with and without progression to myelofibrosis
Methylation profiles of PMF with and without progression to myelofibrosis
PRJNA639574 | ENA
TranscriptomicsShort RNAs expression profiling in circulating CD34+ cells from Primary Myelofibrosis patients and from normal controls pooled bone marrow CD34+ cells.
We report the application of Illumina short RNA sequencing for characterization and discovery of miRNAs and moRNAs, and for identification of differentially expressed small RNAs in circulating CD34+ cells from Primary Myelofibrosis (PMF) patients and from normal controls pooled bone marrow CD34+ cel...
ORGANISM(S): Homo sapiens 
2016-03-17 | E-GEOD-69089 | biostudies-arrayexpress
TranscriptomicsExpression data from patients with Essentiel Thrombocythemia (ET), Polycythemia Vera (PV), Primary Myelofibrosis (PMF) and control subjects
We used microarrays to assess gene expression in patients with ET, PV, and PMF compared to control subjects Total RNA was purified from whole blood and amplified to biotin-labeled aRNA and hybridized to microarray chips.
ORGANISM(S): Homo sapiens 
2012-01-10 | E-GEOD-26049 | biostudies-arrayexpress
Methylation profilingMethylation profiles of PMF with and without progression to myelofibrosis
Patients with prefibrotic PMF have a heterogeneous risk for progression to myelofibrosis. This projects evaluates the potential of comprehensive DNA methylation profiling for predicting fibrotic progress.
ORGANISM(S): Homo sapiens 
2021-02-08 | GSE152519 | GEO
TranscriptomicsGene expression profile of mutated and wild-type PMF CD34+ cells
Primary mielofibrosis (PMF) is a rare chronic myeloproliferative disorder characterized by the accumulation of abnormal megakaryocytes (Mks) in the bone marrow (BM), variable degrees of BM fibrosis, osteosclerosis and angiogenesis, immature myeloid and erythroid cells, and tear-drop erythrocytes in ...
ORGANISM(S): Homo sapiens 
2013-07-23 | GSE41812 | GEO
UnknownVOC source apportionment: How monitoring characteristics influence positive matrix factorization (PMF) solutions.
Not available
S-EPMC10993988 | biostudies-literature
UnknownInterplay between MPIase, YidC, and PMF during Sec-independent insertion of membrane proteins.
Not available
S-EPMC8548208 | biostudies-literature
TranscriptomicsExpression data from patients with Essential Thrombocythemia (ET), Polycythemia Vera (PV), Primary Myelofibrosis (PMF) (untreated)
Microarrays were used to assess gene expression in patients with ET, PV, and PMF before treatment with IFNalpha2.
ORGANISM(S): Homo sapiens 
2017-02-09 | GSE61629 | GEO
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