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ProteomicsRNA Pol II IP-MS and GFP-CUL3 IP-MS by DIA
DIA MS dataset for RNA Polymerase II (Pol II) or GFP-CUL3 co-immunoprecipitants prepared from human DLD-1 SPT5-AID cells treated with +/- NVP-2 +/- auxin (for Pol II IP) or +/- auxin (GFP IP).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-26 | MSV000096543 | MassIVE
GenomicsGRIP-seq data for S. purpuratus, 24hpf embryos
This is the inaugural dataset for the new GRIP-seq method to map cis-regulatory regions genome-wide. This dataset is for the purple sea urchin embryo, S. purpuratus, at 24 hours post fertilization. There are two experimental samples using an anti-Pol(II) antibody to pull down regulatory region-promo...
ORGANISM(S): Strongylocentrotus purpuratus 
2016-06-14 | E-MTAB-3607 | biostudies-arrayexpress
TranscriptomicsRNA Pol II (abcam).S2.GFP_RNAi
modENCODE_submission_3713 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to validate and confirm the locations of 125 chromosomal proteins across the Drosophila mel...
ORGANISM(S): Drosophila melanogaster 
2011-10-12 | E-GEOD-32807 | biostudies-arrayexpress
TranscriptomicsRNA Pol II (abcam).S2.Egg_RNAi
modENCODE_submission_3712 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The goal of these experiments are to validate and confirm the locations of 125 chromosomal proteins across the Drosophila mel...
ORGANISM(S): Drosophila melanogaster 
2011-10-12 | E-GEOD-32806 | biostudies-arrayexpress
GenomicsRNA Pol II (abcam).OR Head Nuclei.Solexa
modENCODE_submission_5124 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of 125 chromosomal proteins across the Drosophila melanogaster genome. The proteins under s...
ORGANISM(S): Drosophila melanogaster 
2013-05-28 | E-GEOD-47304 | biostudies-arrayexpress
GenomicsRNA Pol II (abcam).14-16 hr OR embryo.Solexa
modENCODE_submission_5122 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of 125 chromosomal proteins across the Drosophila melanogaster genome. The proteins under s...
ORGANISM(S): Drosophila melanogaster 
2013-05-28 | E-GEOD-47302 | biostudies-arrayexpress
GenomicsRNA Pol II (abcam).D.mel 3rd Instar Larvae Nuclei.Solexa
modENCODE_submission_5123 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of 125 chromosomal proteins across the Drosophila melanogaster genome. The proteins under s...
ORGANISM(S): Drosophila melanogaster 
2013-05-28 | E-GEOD-47303 | biostudies-arrayexpress
TranscriptomicsHuman nuclear Dicer restricts the deleterious accumulation of endogenous double strand RNA
Dicer is a central enzymatic player in RNA interference (RNAi) pathways that acts to regulate gene expression in nearly all eukaryotes. Although the cytoplasmic function of Dicer is well documented in mammals, there is little known about any possible nuclear function. Here we show that Dicer is pre...
ORGANISM(S): Homo sapiens 
2014-04-10 | E-GEOD-56648 | biostudies-arrayexpress
ProteomicsThe genetic and biochemical basis of human leading strand synthesis
The maintenance of genome stability requires efficient leading strand synthesis by DNA Polymerase Epsilon (Pol). By performing CRISPR genetic screens in cells lacking the POLE4 subunit of Pol we define a genetic map of the factors required to support Pol function in the absence of its accessory subu...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD070472 | Pride
The genetic and biochemical basis of human leading strand synthesis 
TranscriptomicsLong-Term Programming of Antigen-Specific Immunity from Gene Expression Signatures in the PBMC of Rhesus Macaques Immunized with an SIV DNA Vaccine
The primary objective of this study was to evaluate response to a SIV DNA-based vaccine that was adminstered via vivo electroporation (EP) in rhesus macaques to further understand the molecular correlates of protection against SIV. In this study, rhesus macaques were immunized with a DNA vaccine inc...
ORGANISM(S): Macaca mulatta 
2012-02-15 | E-GEOD-35816 | biostudies-arrayexpress
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