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TranscriptomicsTranscription profiling of kidney from rats of SHR/Ola, BN and SHR-18 strains after being provided with drinking water with 1% or 0% sodium chloride
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MIMR-1122 | biostudies-arrayexpress
GenomicsBrg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide binding patterns of these regulators are modulated during B-lineage development remains to be determined. Here, we found that in lymphoid pr...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-66978 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains
Gene expression profiling of peritoneal fat of SHR/01a (spontaneously hypertensive rat), BN-Lx (Brown Norway congenic carrying polydactyly-luxate syndrome)and recombinant inbred (HXB/BXH) 6-week old rat strains.
ORGANISM(S): Rattus norvegicus 
2010-11-18 | E-AFMX-7 | biostudies-arrayexpress
GenomicsSpi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia
Acute leukemia are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant overexpression of the Spi-1/PU.1 transcription factor leads to erythroleukemia. To determine how Spi-1 mechanistically influences the transcriptional pro...
ORGANISM(S): Mus musculus 
2012-06-30 | E-GEOD-33611 | biostudies-arrayexpress
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