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Transcriptomicswnt in human embryonic carcinoma cells
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. Results We have identified target genes of Wnt signaling using microarray technology and human embryonal carcinom...
ORGANISM(S): Homo sapiens 
2005-09-08 | E-GEOD-3262 | biostudies-arrayexpress
TranscriptomicsNormal_human_tissues_genomic_controls
Array hybridizations profiling diverse human tissues; for each array the human tissue RNA is hybridized against a universal reference RNA. Experiments 1-3 are replicates of universal reference RNA vs. genomic DNA hybridizations, used to estimate transcript abundance. Arrays 4-8 are tissue RNA vs. ge...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2194 | biostudies-arrayexpress
TranscriptomicsA DNA microarray survey of gene expression in normal human tissues
Array hybridizations profiling diverse human tissues; for each array the human tissue RNA is hybridized against a universal reference RNA. Series_type: Logical set Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: other. This dataset is ...
ORGANISM(S): Homo sapiens 
2005-02-21 | E-GEOD-2193 | biostudies-arrayexpress
TranscriptomicsFLT3 gene-expression signature in normal karyotype AML
Acute myeloid leukemia with normal karyotype (NK-AML) represents a cytogenetic grouping with intermediate prognosis but substantial molecular and clinical heterogeneity. Within this subgroup, presence of FLT3 (FMS-like tyrosine kinase 3) internal tandem duplication (ITD) mutation predicts less favo...
ORGANISM(S): Homo sapiens 
2008-02-27 | E-GEOD-8043 | biostudies-arrayexpress
TranscriptomicsArray CGH data of 64 prostate cancer specimens
The dataset comprises array CGH data of 64 prostate cancer specimens performed on Stanford cDNA microarrays, to accompany the study of J Lapointe et al (2007). For each array, Channel 2 represents Cy5-labeled prostate genomic DNA, and Channel 1 Cy3-labeled normal male genomic DNA. Set of arrays org...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-6469 | biostudies-arrayexpress
TranscriptomicsBreast Cancer aCGH
Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a genome-wide microarray comparative genomic hybridization (array CGH) analysis of DNA copy number variation in a series of primary human breast tumors. We have profiled DNA...
ORGANISM(S): Homo sapiens 
2005-09-10 | E-GEOD-3281 | biostudies-arrayexpress
TranscriptomicsComparative profiling of primary colorectal carcinomas and liver metastases
PURPOSE: We sought to identify genes of clinical significance to predict survival and the risk for colorectal liver metastasis (CLM), the most common site of metastasis from colorectal cancer (CRC). PATIENTS AND METHODS: We profiled gene expression in 31 specimens from primary CRC and 32 unmatched s...
ORGANISM(S): Homo sapiens 
2011-03-22 | E-GEOD-22834 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of breast cancer cell lines defines relevant tumor models (aCGH)
Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that diversity. In particular, microarray studies have identi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-13914 | biostudies-arrayexpress
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