Sort   by:  
 Page size 
TranscriptomicsExpression data from renal primary epithelial cells
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of multiple fluid-filled cysts that destroy the kidney architecture resulting in end-stage renal failure. Mutations in the ADPKD genes PKD1 and PKD2 account for nearly all the cases of ADPKD. Increased cell prolif...
ORGANISM(S): Rattus norvegicus 
2010-05-19 | E-GEOD-11500 | biostudies-arrayexpress
UnknownThe ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex.
Not available
S-EPMC6832002 | biostudies-literature
UnknownNek8 regulates the expression and localization of polycystin-1 and polycystin-2.
Not available
S-EPMC2391053 | biostudies-literature
GenomicsPolycystin-2 functions as a calcium leak channel under endoplasmic reticulum stress to protect against myocardial ischemia
Polycystin-2 functions as a calcium leak channel under endoplasmic reticulum stress to protect against myocardial ischemia
PRJNA1533467 | ENA
UnknownCryo-EM structure of the polycystin 2-l1 ion channel.
Not available
S-EPMC6056229 | biostudies-literature
UnknownThe ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex
Not available
S-SCDT-EMBOR-2019-48336-T | biostudies-other
UnknownA plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation.
Not available
S-EPMC8933003 | biostudies-literature
UnknownIon channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis.
Not available
S-EPMC12183636 | biostudies-literature
ProteomicsIdentification of biomarkers for PKD1 using urinary exosomes
Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of ESRD. Affected individuals inherit a defective copy of either the PKD1 or PKD2 gene, encoding the proteins polycystin?1 (PC1) or polycystin?2 (PC2) respectively. PC1 and PC2 are secreted on urinary exosome?like vesicles (ELVs)...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-01 | MSV000079547 | MassIVE
UnknownThe polycystin complex mediates Wnt/Ca(2+) signalling.
Not available
S-EPMC4925210 | biostudies-literature
Sort   by:  
 Page size