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GenomicsCompetitive Inhibition and Mutualistic Growth in Polymicrobial Infections: Deciphering Staphylococcus aureus – Acinetobacter baumannii Interaction Dynamics
Competitive Inhibition and Mutualistic Growth in Polymicrobial Infections: Deciphering Staphylococcus aureus – Acinetobacter baumannii Interaction Dynamics
PRJNA1052741 | ENA
TranscriptomicsCompetitive Inhibition and Mutualistic Growth in Polymicrobial Infections: Deciphering Staphylococcus aureus – Acinetobacter baumannii Interaction Dynamics
Staphylococcus aureus (Sa) and Acinetobacter baumannii (Ab) are frequently co-isolated from polymicrobial infections that are severe and recalcitrant to therapy. Here, we apply a combination of wet-lab experiments and in silico modeling to unveil the intricate nature of the Ab/Sa interaction using b...
ORGANISM(S): Staphylococcus aureus subsp. aureus USA300 Acinetobacter baumannii A118 
2024-07-10 | GSE250252 | GEO
ProteomicsMetabolic interplay between Proteus mirabilis and Enterococcus faecalis facilitates polymicrobial biofilm formation and invasive disease
Catheter-associated urinary tract infections (CAUTI) account for 40% of all nosocomial infections and can lead to significant life-threatening complications such as bacteremia. Microbial biofilms play an important role in the development and pathogenesis of CAUTI, and these biofilms are often polymi...
ORGANISM(S): Proteus mirabilis HI4320 Enterococcus faecalis (Streptococcus faecalis) 
2025-05-06 | PXD041693 | Pride
Ionstar Enterococcus faecalis Proteus mirabilis Quantitative proteomics Biofilm 
UnknownInteraction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections.
Not available
S-EPMC5635929 | biostudies-literature
TranscriptomicsTranscriptomic analysis of the influence of arachidonic acid on polymicrobial biofilms of Candida albicans and Pseudomonas aeruginosa
The interaction of clinically relevant microorganisms is the focus of various studies, e.g. the interaction between the pathogenic yeast, Candida albicans, and the bacterium, Pseudomonas aeruginosa and these interactions can alter the outcome of infection, growth dynamics of each species and antimic...
ORGANISM(S): Pseudomonas aeruginosa Candida albicans 
2021-01-31 | GSE136726 | GEO
UnknownInteraction of Bdellovibrio bacteriovorus with Gram-Negative and Gram-Positive Bacteria in Dual Species and Polymicrobial Communities.
Not available
S-EPMC9025206 | biostudies-literature
GenomicsTranscriptomic analysis of the influence of arachidonic acid on polymicrobial biofilms of Candida albicans and Pseudomonas aeruginosa
Transcriptomic analysis of the influence of arachidonic acid on polymicrobial biofilms of Candida albicans and Pseudomonas aeruginosa
PRJNA563341 | ENA
Genomics
Polymicrobial biofilm interaction between Histophilus somni and Pasteurella multocida
PRJNA637966 | ENA
TranscriptomicscRel sang
NF-kB is a transcriptional factor that consists in homo and heterodimers of the large family of Rel subunits. Among the most important functions for NF-kB, initiation of immunological/inflammatory responses and regulation of cell proliferation/apoptosis which are the major features of severe infecti...
ORGANISM(S): Mus musculus 
2011-10-14 | E-MEXP-2944 | biostudies-arrayexpress
TranscriptomicsSynergy between the periodontal pathogens Tannerella forsythia and Porphyromonas gingivalis enhances host inflammatory signaling to polymicrobial biofilms and induces transcriptomic remodeling in T. forsythia II
Periodontitis is a devastating polymicrobial biofilm disease for which no targeted therapies currently exist. Although P. gingivalis is considered the keystone pathogen of periodontitis, how its synergistic interaction with the red-complex pathogen Tannerella forsythia shapes biofilm community dynam...
ORGANISM(S): Porphyromonas gingivalis Tannerella forsythia 
2026-09-08 | GSE327566 | GEO
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