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ProteomicsPlasma and Extracellular Vesicle Proteomic Signatures of traumatic brain injury (TBI) in Polytrauma
This study aimed to identify TBI-specific proteomic signatures in a heterogeneous cohort of critically injured polytrauma patients by analyzing the total plasma proteome and an extracellular vesicle (EV)-enriched plasma protein fraction. Severely injured adult trauma patients (ISS ≥16) were allo...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD079127 | Pride
Traumatic brain injury  extracellular vesicles  biomarkers  proteomics  polytrauma 
GenomicsWhole transcriptome analysis of endothelial cells (HUVECs) after treatment with plasma-sEVs from polytrauma patients
Whole transcriptome analysis of endothelial cells (HUVECs) after treatment with plasma-sEVs from polytrauma patients
PRJNA722438 | ENA
UnknownIs polytrauma really just a simple accident? Recurrent characteristic of polytrauma.
Not available
S-EPMC11600709 | biostudies-literature
GenomicsPlasma and Extracellular Vesicle small RNAs sequencing -severe Traumatic Brain Injury Patients,polytrauma patients and healthy controls
Plasma and Extracellular Vesicle small RNAs sequencing -severe Traumatic Brain Injury Patients,polytrauma patients and healthy controls
PRJNA1439852 | ENA
UnknownStandards of fracture care in polytrauma: results of a Europe-wide survey by the ESTES polytrauma section.
Not available
S-EPMC11249422 | biostudies-literature
GenomicsPlasma and Extracellular Vesicle small RNAs sequencing -severe Traumatic Brain Injury Patients,polytrauma patients and healthy controls
This study aimed to compare plasma- and extracellular vesicles (EVs)-associated microRNAs (miRNAs) signatures in patients with severe TBI, polytrauma and healthy controls.
ORGANISM(S): Homo sapiens 
2026-05-18 | GSE325396 | GEO
TranscriptomicsWhole transcriptome analysis of endothelial cells (HUVECs) after treatment with plasma-sEVs from polytrauma patients
To assess inflammation associated gene expression in endothelial cells mediated by small extracellular vesicles (sEVs), HUVECs were treated for 8hrs with plasma-Evs isolated from polytrauma patients 4 and 24hrs after trauma and healthy probands.
ORGANISM(S): Homo sapiens 
2021-04-17 | GSE172210 | GEO
UnknownAcute Gastrointestinal Injury in Polytrauma: Special Attention to Elderly Patients.
Not available
S-EPMC11413898 | biostudies-literature
GenomicsMiR-146a-5p and miR-146b-5p limit IL-1beta-mediated inflammation in adipose tissue during polytrauma
MicroRNAs (miRNAs) are small non-coding RNAs and play a crucial role in the regulation of inflammation. White adipose tissue (WAT) covers the body and internal organs in subcutaneous and visceral fat depots, respectively, and represents an important source of circulating miRNAs. The role of WAT and ...
ORGANISM(S): synthetic construct Mus musculus 
2026-02-17 | GSE302289 | GEO
UnknownPredicting the complexity and mortality of polytrauma patients with machine learning models.
Not available
S-EPMC11004111 | biostudies-literature
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