Sort   by:  
 Page size 
TranscriptomicsExpression data from WT mice and bitransgenic Pdx1-cre/Kras*A mice bearing Pancreatic Ductal Adenocarcinoma
We have carried out transcriptional profile analysis in WT MICE and bitransgenic Pdx1-cre/Kras*A MICE baring Pancreatic Ductal Adenocarcinoma Mouse models faithfully simulating human cancer are valuable for genetic identification of potential drug-targets but, among them, the most advantageous for ...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-53659 | biostudies-arrayexpress
UnknownIdentification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes.
Not available
S-EPMC7780151 | biostudies-literature
TranscriptomicsRole of Notch signaling pathway in urothelial cancer
The Notch signaling pathway controls cell fates through interactions between neighboring cells by positively or negatively affecting, in a context-dependent manner, processes of proliferation, differentiation, and apoptosis1. It has been implicated in human cancer both as an oncogene and a tumor sup...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54589 | biostudies-arrayexpress
UnknownIdentification of a dynamic gene regulatory network required for pluripotency factor-induced reprogramming of mouse fibroblasts and hepatocytes
Not available
S-SCDT-EMBOJ-2019-102236 | biostudies-other
TranscriptomicsProtracted p53-independent stimulation of p21WAF1/Cip1 fuels genomic instability by deregulating the replication licensing machinery
The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is the prototype downstream effector of the tumor suppressor protein p53. Yet, evidence from human cancer and mice models, imply that p21WAF1/Cip1, under certain conditions, can exercise oncogenic activity. The mechanism behind this behavior is stil...
ORGANISM(S): Homo sapiens 
2016-05-15 | E-GEOD-62166 | biostudies-arrayexpress
TranscriptomicsExpression data from Vulvar, Cervical, Endometrial Carcinoma tissue
A growing number of studies on gynecological cancers (GCs) have revealed potential gene markers associated either with the pathogenesis and progression of the disease on representing putative targets for therapy and treatment of cervical (CC), endometrial (EC) and vulvar cancer (VC). However, quite ...
ORGANISM(S): Homo sapiens 
2015-07-26 | E-GEOD-63678 | biostudies-arrayexpress
TranscriptomicsExpression data from knockdown and Sendai virus induction experiments in Human cells
We have carried out transcriptional profile analysis in macroH2A knockdown cells (Namalwa B cells and HeLa cells) and demonstrated that this histone variant plays positive and negative roles in transcription. We also demonstrated the role of macroH2A in regulating the response to Sendai Virus infec...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-53103 | biostudies-arrayexpress
Unknown3-Hydroxyanthralinic acid metabolism controls the hepatic SREBP/lipoprotein axis, inhibits inflammasome activation in macrophages, and decreases atherosclerosis in Ldlr-/- mice.
Not available
S-EPMC7519886 | biostudies-literature
UnknownCoordinated repression of ZGA genes by methyltransferase EHMT2 via LINE1 regulatory elements
Not available
S-SCDT-10_1038-S44319-025-00657-5 | biostudies-other
Sort   by:  
 Page size