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UnknownSLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.
Not available
S-EPMC3138634 | biostudies-literature
TranscriptomicsFunctional enhancers at the gene-poor 8q24 cancer-linked locus
Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their biological activities have been unknown. Here we profiled a 5-megabase chromatin segment encompassin...
ORGANISM(S): Homo sapiens 
2009-12-18 | E-GEOD-19561 | biostudies-arrayexpress
TranscriptomicsRNA expression at chromosome 8q24 in human colon
An inherited variant on chromosome 8q24, rs6983267, is significantly associated with cancer pathogenesis. We present evidence that this region is a transcriptional enhancer, that the risk region physically interacts with the MYC proto-oncogene, and that the alleles of rs6983267 differentially bind t...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16228 | biostudies-arrayexpress
UnknownCAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants.
Not available
S-EPMC4746056 | biostudies-literature
UnknownGenome-wide association study identifies multiple risk loci for renal cell carcinoma.
Not available
S-EPMC5472706 | biostudies-literature
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