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GenomicsThe Histone H3 Lysine 9 Methyltransferases G9a and GLP Regulate Polycomb Repressive Complex 2-Mediated Gene Silencing [ChIP-Seq]
G9a/GLP and Polycomb Repressive Complex 2 (PRC2) are two major epigenetic silencing machineries, which in particular methylate histone H3 on lysines 9 and 27 (H3K9 and H3K27), respectively. Although evidence of a crosstalk between H3K9 and H3K27 methylations has started to emerge, their actual inter...
ORGANISM(S): Mus musculus 
2014-01-03 | E-GEOD-46536 | biostudies-arrayexpress
TranscriptomicsThe Histone H3 Lysine 9 Methyltransferases G9a and GLP Regulate Polycomb Repressive Complex 2-Mediated Gene Silencing [RNA-Seq]
G9a/GLP and Polycomb Repressive Complex 2 (PRC2) are two major epigenetic silencing machineries, which in particular methylate histone H3 on lysines 9 and 27 (H3K9 and H3K27), respectively. Although evidence of a crosstalk between H3K9 and H3K27 methylations has started to emerge, their actual inter...
ORGANISM(S): Mus musculus 
2014-01-03 | E-GEOD-49669 | biostudies-arrayexpress
TranscriptomicsRNA-seq of naive and primed ES cells (NHSM)
Here we propose a set of molecular criteria for evaluating the naive human pluripotent state. We show by RNA-seq that transcription of transposable elements provides a sensitive measure of the concordance between pluripotent stem cells and early human development. RNA-seq of 3 naive ES samples in NH...
ORGANISM(S): Homo sapiens 
2016-08-16 | E-GEOD-85689 | biostudies-arrayexpress
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