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Transcriptomicssmall RNAnext Generation Sequencing of bone marrow-derived macrophages treated in M-CSF withdrawal medium
The goal of this study is to investigate the presence of novel small RNAs in apoptotic macrophage Method: cultured mouse (bl6 line) bone marrow were differentiated in for 7 days in conditioned medium, in preence of Macrophage-Colony Stimulating Factor (M-CSF). M-CSF also stimulates the survive of ma...
ORGANISM(S): Mus musculus 
2015-09-16 | E-GEOD-47408 | biostudies-arrayexpress
TranscriptomicsPHF8 mediates histone demethylation events in cell cycle progression
This SuperSeries is composed of the following subset Series: GSE22477: PHF8 mediates histone demethylation events in cell cycle progression [expression] GSE22478: PHF8 mediates histone demethylation events in cell cycle progression [ChIP-Seq] Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-22400 | biostudies-arrayexpress
TranscriptomicsGene expression profiling reveals activation of the FA/BRCA pathway in advanced squamous cervical cancer with intrinsic resistance and therapy failure
Twenty-one patients with locally advanced squamous cell carcinoma were enrolled in this study. Primary biopsies harvested prior to therapy were divided according to the patientM-bM-^@M-^Ys 6 months clinical response and analyzed for whole human gene expression (Agilent). A 2859-gene signature was id...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-56363 | biostudies-arrayexpress
TranscriptomicsALKBH5 is a New Mammalian RNA Demethylase
N6-methyladenosine (m6A) is the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Here we report ALKBH5 as a new mammalian demethylase that oxidatively removes the m6A modification in mRNA in vitro and inside cells. This demethylation activity of ALKBH5 significantly...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-40132 | biostudies-arrayexpress
GenomicsPHF8 mediates histone demethylation events in cell cycle progression [ChIP-Seq]
While reversible histone modifications are linked to an ever-expanding range of biological functions, the demethylases for histone H4 lysine 20 and their potential regulatory roles remain unknown. Here, we report that the PHD and Jumonji C (JmjC) domain-containing protein, PHF8, while utilizing mul...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-22478 | biostudies-arrayexpress
UnknownThe Effect of Incidental Consolidation on Management and Outcomes in COPD Exacerbations: Data from the European COPD Audit.
Not available
S-EPMC4516303 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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