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TranscriptomicsGene expression signature overlap between shETV1 and BRD32048 in LNCaP and SK-MEL-28
Identification of BRD32048 as an inhibitor of ETV1 oncogenic transcription factor. This compound was indentified by small molecule mcroarray (a binding assay). It was able to consistently inhibit an ETV1-dependent MMP1-driven luciferase signal. Its direct binding was validated by Suface plasmon reso...
ORGANISM(S): Homo sapiens 
2013-11-07 | E-GEOD-52154 | biostudies-arrayexpress
TranscriptomicsRNA-seq of enriched barley stomatal complexes versus total leaves
We intend to identify transporters and their regulators involved in barley stomatal movement as well as components of the ABA signaling pathway. We isolated epidermal peels where only stomatal guard cells and their subsidiary cells survived, while other epidermal cell were mechanically disrupted and...
ORGANISM(S): Hordeum vulgare 
2018-02-21 | E-MTAB-5877 | biostudies-arrayexpress
TranscriptomicsRNAseq of Anopheles gambiae mosquito lines selected for several generations with different agrochemical mixtures
Gene expression changes and polymorphisms were investigated in genetically related mosquito lines maintained for 30 generations under four different selection regimes. All mosquito line derived from the same parental line (Anopheles gambiae Tiassale line from Ivory coast). Selection regimes were as ...
ORGANISM(S): Anopheles gambiae 
2023-05-01 | E-MTAB-12756 | biostudies-arrayexpress
GenomicsLocalization of the Rb tumor suppressor in MEFs during reprogramming to iPS and the consequence of Rb loss on the transcriptional profile and histone landscape in these cells
The reprogramming of differentiated cells to an embryonic stem cell-like state provides a powerful system to explore fundamental mechanisms of development, including how mammalian cells establish and maintain pluripotency and long-term self-renewal capability. Based on the similarities between embry...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-40594 | biostudies-arrayexpress
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