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GenomicsVesicular transplantation of gasdermin pores propagates pyroptosis
Vesicular transplantation of gasdermin pores propagates pyroptosis
PRJNA1161397 | ENA
TranscriptomicsVesicular transplantation of gasdermin pores propagates pyroptosis
Pyroptosis—inflammatory cell death mediated by gasdermins (GSDM)—plays crucial roles in antimicrobial defense and inflammatory diseases. Pyroptosis results in the release of proinflammatory molecules, including damage-associated molecular patterns (DAMPs). However, our understanding of the consequen...
ORGANISM(S): Mus musculus 
2025-01-07 | GSE277224 | GEO
TranscriptomicsRNA expression for dcr1D, rdp1D, ago1D and swi6D
RNA interference (RNAi) pathways are prevalent throughout the eukaryotic kingdom and well known to regulate gene expression on a post-transcriptional level in the cytoplasm. Less is known about possible functions of RNAi in the nucleus. In the fission yeast Schizosaccharomyces pombe, RNAi is crucial...
ORGANISM(S): Schizosaccharomyces pombe 
2012-03-19 | E-GEOD-36113 | biostudies-arrayexpress
GenomicsNuclear transport surveillance of p53 by nuclear pores in glioblastoma
Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
PRJNA896119 | ENA
GenomicsFG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [smallRNA-seq]
FG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [smallRNA-seq]
PRJNA1235205 | ENA
GenomicsFG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [RNA-seq]
FG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [RNA-seq]
PRJNA1235204 | ENA
TranscriptomicsExpression data changes induced by one round migration through 3 μm pores in T-ALL cells
One round migration through 3 μm pores promotes changes in transcription of T-ALL cells
ORGANISM(S): Homo sapiens 
2023-10-12 | GSE239463 | GEO
TranscriptomicsExpression in arp6 and swr1 deletion mutants
Actin-related proteins are ubiquitous components of chromatin remodelers, and are conserved from yeast to man. We have examined the role of the budding yeast actin-related protein Arp6 in gene expression, both as a component of the SWR1 complex (SWR-C) and in its absence. We mapped Arp6-binding site...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-01 | E-GEOD-17780 | biostudies-arrayexpress
GenomicsFG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [smallRNA-seq]
Condensates that accumulate small RNA biogenesis factors (nuage) are common in germ cells and often associate with nuclei. In the C. elegans germline, P granules overlay large clusters of nuclear pores and this organization has been proposed to facilitate surveillance of nascent transcripts by Argon...
ORGANISM(S): Caenorhabditis elegans 
2025-03-16 | GSE291761 | GEO
TranscriptomicsFG repeats drive co-clustering of nuclear pores and P. granules in the C elegans germline [RNA-seq]
Condensates that accumulate small RNA biogenesis factors (nuage) are common in germ cells and often associate with nuclei. In the C. elegans germline, P granules overlay large clusters of nuclear pores and this organization has been proposed to facilitate surveillance of nascent transcripts by Argon...
ORGANISM(S): Caenorhabditis elegans 
2025-03-16 | GSE291760 | GEO
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