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MetabolomicsCesarean section alters the postnatal development of the gut microbiome and metabolome of male Wistar rats

Background: The gut microbiome, a complex community of bacteria, viruses, fungi, and protozoa, matures alongside its host. In humans, the birth mode, vaginal delivery (VD) or cesarean section (CS), is a major determinant of early microbial colonization. However, it remains unclea...

2026-07-30 | MTBLS7384 | MetaboLights
MetabolomicsMulti-omics Insights into Postnatal Skeletal Muscle Development in Duroc Pigs

Skeletal muscles, accounting for 40% of mammalian body mass, exhibit pronounced heterogeneity due to distinct anatomical locations. Animal husbandry excessively focuses on longissimus dorsi (LDM) development, while neglecting other muscles. In this study, we integrated Bulk RNA Sequencing (bulk R...

2025-09-09 | MTBLS12963 | MetaboLights
MetabolomicsRole of breast milk lipid composition in postnatal brain development.

Lipids in the brain play a crucial role as structural and signaling molecules, accounting for approximately 60% of the brain’s dry weight. Several lipid classes exhibit concentration profile differences between humans and other species, including closely related primates, with the most pronounced...

2025-09-25 | MTBLS12481 | MetaboLights
MetabolomicsEarly postnatal metabolic profile in neonates with different birth weight status: A pilot study

INTRODUCTION: Restricted or enhanced intrauterine growth is associated with elevated risks of early and late metabolic problems in humans. Metabolomics based on amino acid and carnitine/acylcarnitine profile may have a role in fetal and early postnatal energy metabolism. In this ...

2021-04-28 | MTBLS2376 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (GC-MS assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS288 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS pos assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS286 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS neg assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS287 | MetaboLights
MetabolomicsMetabolomic landscape of fetal organs development during late gestation in mice
Metabolism is the critical basis for mammalian physiological functions. The systematic metabolic characteristics of major organ development during late gestation to adapt to postnatal environmental changes are still absent. Here, we detected metabolic patterns of the mouse fetal organs, including th...
2025-08-23 | MTBLS12560 | MetaboLights
MetabolomicsIntegrative multi-omics analysis of rumen development in early-life yaks
This study investigates the developmental changes in the rumen of early-life yaks using integrative metagenomics, metabolomics, histology, fermentation profiling, and single-cell transcriptomics. Rumen fluid and epithelial tissue samples collected from yaks at 1, 6, and 12 months of age were analyze...
2026-04-21 | MTBLS14340 | MetaboLights
TranscriptomicsTranscription profiling of rat extraocular and gastrocnemius/soleus muscles during postnatal development
Conserved and muscle group-specific gene expression patterns shape postnatal development of the novel extraocular muscle phenotype. Comparison of postnatal development of extraocular and hindlimb muscle between birth and P45.
ORGANISM(S): Rattus norvegicus 
2007-10-12 | E-GEOD-903 | biostudies-arrayexpress
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