Sort   by:  
 Page size 
Transcriptomicsc-MYC target genes in HUVEC
siRNA mediated knock-down of c-MYC vs. scrambled control in human umbilical vein endothelial cells (HUVEC).
ORGANISM(S): Homo sapiens 
2016-01-11 | E-MTAB-4025 | biostudies-arrayexpress
TranscriptomicsFOXO1 target genes in HUVEC
Adenoviral expression of a constitutive active FOXO1 vs. control GFP in human umbilical vein endothelial cells (HUVEC). Expression analysis 16 h after transduction.
ORGANISM(S): Homo sapiens 
2016-01-11 | E-MTAB-4023 | biostudies-arrayexpress
ProteomicsA YAP/TAZ-TEAD signaling module links endothelial nutrient acquisition to angiogenic growth
Angiogenesis, the process by which endothelial cells (ECs) form new blood vessels from existing ones, is intimately linked to the tissue's metabolic milieu and often occurs at nutrient-deficient sites. However, ECs rely on sufficient metabolic resources to support growth and proliferation. How endot...
ORGANISM(S): Homo sapiens (Human) 
2022-05-08 | PXD026872 | Pride
Yap/taz-tead signaling Mtorc1 Endothelial cells Angiogenesis Nutrient acquisition 
TranscriptomicsDeubiquitinase USP10 regulates Notch signaling in the endothelium
Notch signaling is critical for vascular morphogenesis by co-determining the sprouting behavior of endothelial cells. Here, we investigate the function of ubiquitin-specific peptidase 10 (USP10) in regulation of the turnover of the NOTCH1 intracellular domain. HUVEC were transfected with scrambled o...
ORGANISM(S): Homo sapiens 
2019-04-26 | E-MTAB-7774 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse VE-cadherin null cell line vs contrik
In order to identify genes regulated by VE-cadherin expression, we compared a mouse VE-cadherin null cell line (VEC null) with the same line reconstituted with VE-cadherin wild type cDNA (VEC positive). The morphological and functional properties of these cell lines were described previously [Lampug...
ORGANISM(S): Mus musculus 
2008-10-20 | E-GEOD-11674 | biostudies-arrayexpress
ProteomicsEndothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2
Activation of endothelial YAP/TAZ signaling is crucial for physiological and pathological angiogenesis. The mechanisms of endothelial YAP/TAZ regulation are, however, incompletely understood. Here we report that the protocadherin FAT1 acts as a critical upstream regulator of endothelial YAP/TAZ whic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-14 | MSV000091279 | MassIVE
Sort   by:  
 Page size