Sort   by:  
 Page size 
TranscriptomicsDiscovery of the p53 targetome in MCF7 cells from RNA-seq and ChIP-seq data
This SuperSeries is composed of the SubSeries listed below. iRegulon: from a gene list to a gene regulatory network using large motif and track collections. RekinM-bM-^@M-^Ys Janky, Annelien Verfaillie, Hana ImrichovM-CM-!, Bram Van de Sande, Laura Standaert, Valerie Christiaens, Gert Hulselmans, ...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-47043 | biostudies-arrayexpress
GenomicsIdentification of lineage-specific cis-regulatory modules associated with variation in transcription factor binding and chromatin activity using Ornstein-Uhlenbeck models
Whole-chromatin profile (FAIRE-seq) in three Drosophila species (D. melanogaster, D. pseudoobscura and D. virilis) in eye-antennal imaginal discs at the stage of third instar wandering larvae. By the use of Ornstein-Uhlenbeck methods, we assess the evolutionary forces acting on regulatory elements (...
ORGANISM(S): Drosophila pseudoobscura 
2015-06-17 | E-GEOD-59706 | biostudies-arrayexpress
GenomicsDiscovery of Transcription Factors and Regulatory Regions Driving In Vivo Tumor Development by ATAC-seq and FAIRE-seq Open Chromatin Profiling
Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regions or accessi...
ORGANISM(S): Drosophila melanogaster 
2015-02-13 | E-GEOD-59078 | biostudies-arrayexpress
TranscriptomicsAn ectopic network of transcription factors regulated by Hippo signaling drives growth and invasion of a malignant tumor model [larval imaginal discs (eye, wing and leg)]
Cancer cells have abnormal gene expression patterns, however, the transcription factors and the architecture of the regulatory network that drive cancer specific gene expression profiles is often not known. Here we studied a model of Ras-driven invasive tumorigenesis in Drosophila larval epithelial ...
ORGANISM(S): Drosophila melanogaster 
2016-06-10 | E-GEOD-81272 | biostudies-arrayexpress
TranscriptomicsAn ectopic network of transcription factors regulated by Hippo signaling drives growth and invasion of a malignant tumor model [larval wild type discs]
Cancer cells have abnormal gene expression profiles, however, the transcription factors and the architecture of the regulatory network that drive cancer specific gene expression is often not known. Here we studied a model of Ras-driven invasive tumorigenesis in Drosophila epithelial tissues and comb...
ORGANISM(S): Drosophila melanogaster 
2016-06-10 | E-GEOD-71353 | biostudies-arrayexpress
TranscriptomicsAn ectopic network of transcription factors regulated by Hippo signaling drives growth and invasion of a malignant tumor model [larval imaginal discs]
Cancer cells have abnormal gene expression profiles, however, the transcription factors and the architecture of the regulatory network that drive cancer specific gene expression is often not known. Here we studied a model of Ras-driven invasive tumorigenesis in Drosophila epithelial tissues and comb...
ORGANISM(S): Drosophila melanogaster 
2016-06-10 | E-GEOD-71350 | biostudies-arrayexpress
Sort   by:  
 Page size