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Identification of target genes of the POU-transcription factor Oct-6 in macrophages after poly(I:C) treatment WT and Oct-6-/- fetal-liver macrophages were treated with poly(I:C) for 8 hours or were left untreated (3 independent expreiments = biological replicates). 200 genes differentially regulated...
ORGANISM(S): Mus musculus 
Purpose: Understand how the misexpression of key sensory cell determinant POU IV affects cell type specification of various sensory neurons in the peripheral nervous system in Ciona. Methods: CesA>POU IV (2.5ng/l) + CesA>GFP (5.0ng/l) injected eggs and control eggs were fertilized side by side, an...
ORGANISM(S): Ciona intestinalis 
2021-12-29 | GSE192645 | GEO
RPF-1 binds promoters of genes modulated by its induction in HEK/RPF-1 transfectant Chromatin IP (ChIP) combined to chromatin array analysis (ChIP-chip) shows that RPF-1 transcription factor bind to promoter elements of genes repressed or activated by RPF-1 expression Comparison of cells induced for...
ORGANISM(S): Homo sapiens 
RPF-1, a transcription factors encoded by POU6F2 gene, appears to be expressed in the developing nervous system and embryonic kidney. We generated a stable HEK/RPF-1 transfectant expressing the protein in a tetracycline (Tet)-dependent induction and addressed the whole transcriptome regulated by RPF...
ORGANISM(S): Homo sapiens 
Single-cell RNA-seq data for control and POU IV-misexpressed Ciona intestinalis embryos at late tailbud (LTB) stage
The impact of pesticides on amphibian metamorphosis may vary depending on developmental stage of individuals during the exposure period. Some anurans experience increased rates of development when exposure to the insecticide carbaryl occurs later in larval development. We exposed developing northern...
ORGANISM(S): Rana clamitans 
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