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TranscriptomicsThe effect of PPARa siRNA on endothelial cells treated with fenofibrate
Fenofibrate is a synthetic ligand for the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha, but there are reports that fenofibrate affects endothelial cells in PPARa-independent manner. In order to identify PPARa-dependently and PPARa-independently regulated transcripts we ge...
ORGANISM(S): Homo sapiens 
2009-08-24 | E-GEOD-15482 | biostudies-arrayexpress
GenomicsGenome-wide profiling of PPARA in PPARA agonist-treated mouse livers [ChIP-seq]
Genome-wide profiling of PPARA in PPARA agonist-treated mouse livers [ChIP-seq]
PRJNA645713 | ENA
TranscriptomicsTranscriptome analysis of the injected Ppara-KO mice overexpressing TFEB specifically in liver
Expression data from Ppara (peroxisome proliferator activated receptor alpha) KO mice injected with TFEB specifically in liver. In order to identify the effects of TFEB overexpression together with Ppara absence on the liver transcriptome, we performed Affymetrix Gene-Chip hybridization experiments ...
ORGANISM(S): Mus musculus 
2013-04-20 | E-GEOD-41140 | biostudies-arrayexpress
GenomicsExpression profiling in liver of wild type and Ppara-null mice treated with PPARA agonists [RNA-seq]
Expression profiling in liver of wild type and Ppara-null mice treated with PPARA agonists [RNA-seq]
PRJNA645712 | ENA
GenomicsGene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
PRJNA645710 | ENA
TranscriptomicsTranscription profiling of mouse myocardium from gnotobiotic wild-type and Ppara-/- animals
Germ free (GF) and conventionalized (CONV-D) wild-type C57Bl/6 male mice in the CARB-fed, 24h fasted, and 30d trained states; plus GF and CONV-D CARB-fed Ppara-/- mice. CARB-fed indicates a standard polysaccharide-rich mouse chow diet. CONV-D mice are those that received a microbiota transplant fro...
ORGANISM(S): Mus musculus 
2009-07-01 | E-GEOD-14929 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of white adipose tissue from wild type and Ppara KO mice treated with the adrb3 agonist CL 316243 to understand the metabolic and cellular plasticity in the tissue.
Time course of gene expression changes in white fat of wildtype and Ppara KO mice during treatment with the adrb3 agonist CL 316243.
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-2131 | biostudies-arrayexpress
GenomicsGenome-wide profiling of PPARA in PPARA agonist-treated mouse livers [ChIP-seq]
To clarify mouse PPARA autoinduction and hepatocyte proliferation signaling pathways, genome-wide distribution of PPARA in the liver of PPARA agonist-treated mice compared to Vehicle was analyzed.
ORGANISM(S): Mus musculus 
2022-04-05 | GSE154276 | GEO
GenomicsVitamin B2 enables PPARa regulation of fasting glucose availability
Vitamin B2 enables PPARa regulation of fasting glucose availability
PRJNA849596 | ENA
TranscriptomicsmRNA profiling reveals divergent roles of PPARa and PPARÃ?/d in regulating mouse liver gene expression (PPARa samples)
Little is known about the role of the transcription factor PPARÃ?/d in liver. Here we set out to better elucidate the function of PPARÃ?/d in liver by comparing the effect of PPARa and PPARÃ?/d deletion using whole genome transcriptional profiling and analysis of plasma and liver metabolites. In fed...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-17863 | biostudies-arrayexpress
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