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GenomicsLysosome-dependent LXR and PPARdelta Activation upon Efferocytosis in Human Macrophages
Lysosome-dependent LXR and PPARdelta Activation upon Efferocytosis in Human Macrophages
PRJNA715460 | ENA
UnknownPPARdelta regulates glucose metabolism and insulin sensitivity.
Not available
S-EPMC1413918 | biostudies-literature
UnknownPPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis.
Not available
S-EPMC2393800 | biostudies-literature
UnknownPPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
Not available
S-EPMC3779681 | biostudies-literature
TranscriptomicsLysosome-dependent LXR and PPARdelta Activation upon Efferocytosis in Human Macrophages
Efferocytosis is critical for tissue homeostasis, as its deregulation is associated with several autoimmune pathologies. While engulfing apoptotic cells, phagocytes activate transcription factors, such as peroxisome proliferator-activated receptors (PPAR) or liver X receptors (LXR) that orchestrate ...
ORGANISM(S): Homo sapiens 
2021-05-26 | GSE169160 | GEO
GenomicsAnalysis of gene expression in wildtype and PPARdelta knockout naïve CD4+ T cells
Analysis of gene expression in wildtype and PPARdelta knockout naïve CD4+ T cells
PRJNA482152 | ENA
TranscriptomicsMicroarray analysis of cooperation between AMPK and PPARdelta in primary human macrophages
Primary human macrophages were transduced with control (CV) or lentiviral particles coding for constitutively active (CA)-AMPKalpha1 (AMPK OE) for 48 hours and treated with 100 nM PPARdelta agonist GW501516 for additional 24 hours. Total RNA was isolated with RNeasy total RNA cleanup kit (Qiagen) a...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-MTAB-2524 | biostudies-arrayexpress
UnknownCOX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation.
Not available
S-EPMC2118704 | biostudies-literature
UnknownAdipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
Not available
S-EPMC2586840 | biostudies-literature
UnknownPPARdelta promotes wound healing by up-regulating TGF-beta1-dependent or -independent expression of extracellular matrix proteins.
Not available
S-EPMC3829036 | biostudies-literature
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